Determination of oxalate concentration in blood

The methods used for determination of oxalate in blood are reviewed, and the advantages and disadvantages of the two basic approaches--direct methods and in vivo isotope-dilution techniques--are compared. Possible reasons for the previous discrepancies between direct and isotopic methods are discuss...

Full description

Saved in:

Bibliographic Details
Published in:	Clinical chemistry (Baltimore, Md.) Vol. 34; no. 8; p. 1540
Main Authors:	Costello, J, Landwehr, D M
Format:	Journal Article
Language:	English
Published:	England 01-08-1988
Subjects:	Female Humans Male Methods Oxalates - blood Oxalic Acid Protein Binding Reference Values Renal Dialysis Sex Characteristics
Online Access:	Get more information
Tags:	Add Tag No Tags, Be the first to tag this record!

Description
Summary:	The methods used for determination of oxalate in blood are reviewed, and the advantages and disadvantages of the two basic approaches--direct methods and in vivo isotope-dilution techniques--are compared. Possible reasons for the previous discrepancies between direct and isotopic methods are discussed, as are the effects of protein binding, sample handling, and storage conditions on oxalate values in plasma. Necessary precautions for obtaining reproducible results are presented. We recommend and critically review several direct methods, and describe the application of a direct method for oxalate determination in some other biological fluids.
ISSN:	0009-9147
DOI:	10.1093/clinchem/34.8.1540