The nucleotide sequence of the tnpA gene of Tn21

The nucleotide sequence of the tnpA gene of Tn21 is presented. The transposase encoded by this gene is exactly the same length (988 amino acids) as the Tn501 transposase (4), and shows 72% homology overall with this protein, with greater homology towards the C-terminus. The sequence of the transposa...

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Bibliographic Details
Published in:	Nucleic acids research Vol. 15; no. 4; pp. 1799 - 1806
Main Authors:	WARD, E, GRINSTED, J
Format:	Journal Article
Language:	English
Published:	Oxford Oxford University Press 25-02-1987
Subjects:	Amino Acid Sequence Base Sequence Biological and medical sciences Cloning, Molecular DNA Restriction Enzymes DNA Transposable Elements Fundamental and applied biological sciences. Psychology Genes Genes, Bacterial Genes. Genome Molecular and cellular biology Molecular genetics Nucleotidyltransferases - genetics Sequence Homology, Nucleic Acid Transposases Gene Primary structure Transposon
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Summary:	The nucleotide sequence of the tnpA gene of Tn21 is presented. The transposase encoded by this gene is exactly the same length (988 amino acids) as the Tn501 transposase (4), and shows 72% homology overall with this protein, with greater homology towards the C-terminus. The sequence of the transposase is discussed in the context of the evolution of Class II transposable elements and of the characteristics of the enzyme's action.
Bibliography:	ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23
ISSN:	0305-1048 1362-4962
DOI:	10.1093/nar/15.4.1799