Ulcerative colitis-specific delivery of keratinocyte growth factor by neutrophils-simulated liposomes facilitates the morphologic and functional recovery of the damaged colon through alleviating the inflammation

Keratinocyte growth factor (KGF) was effective to treat ulcerative colitis. However, its poor stability and unspecific distribution toward inflamed bowel were two important obstacles hindering its consistent efficacy. Herein, KGF was firstly encapsulated into the liposomes (KGF-Lips) to improve its...

Full description

Bibliographic Details

Published in:	Journal of controlled release Vol. 299; pp. 90 - 106
Main Authors:	Zhao, Ying-Zheng, ZhuGe, De-Li, Tong, Meng-Qi, Lin, Meng-Ting, Zheng, Ya-Wen, Jiang, Xue, Yang, Wai-Geng, Yao, Qing, Xiang, Qi, Li, Xiao-Kun, Xu, He-Lin
Format:	Journal Article
Language:	English
Published:	Netherlands Elsevier B.V 10-04-2019
Subjects:	Inflammation Keratinocyte growth factor Liposomes Neutrophil membrane Ulcerative colitis Neutrophil membrane Inflammation Keratinocyte growth factor Liposomes Ulcerative colitis
Online Access:	Get full text
Tags:	Add Tag No Tags, Be the first to tag this record!