Risk factors associated with hepatitis C among patients co-infected with human immunodeficiency virus: a case-control study

• Published in: The American journal of tropical medicine and hygiene Vol. 72; no. 6; p. 762
• Main Authors: Mendes-Correa, Maria Cássia Jacintho, Barone, Antonio Alci, Gianini, Reinaldo José
• Format: Journal Article
• Language: English
• Published: United States 01-06-2005
• Subjects: Adult; Case-Control Studies; Confidence Intervals; Female; Hepatitis C - complications; Hepatitis C - epidemiology; HIV Infections - complications; HIV Infections - epidemiology; Humans; Male; Middle Aged; Odds Ratio; Risk Factors
• ISSN: 0002-9637
• DOI: 10.4269/ajtmh.2005.72.762

A case-control study was carried out to assess the risk factors associated with hepatitis C in patients infected with human immunodeficiency virus. One hundred eighteen patients tested positive for hepatitis C virus (HCV) and were included as cases, and 117 tested negative for HCV and were included as controls. Information was collected through a questionnaire. The risk factors that showed a significant association with co-infection by multivariate analysis were an age of 30-39 years (odds ratio [OR] = 4.65, 95% confidence interval [CI] = 1.31-16.43), an age of 40-49 years (OR = 6.48, 95% CI = 1.70-24.78), an age > 50 years (OR = 7.50, 95% CI = 1.54-36.68), use of intravenous drugs (OR = 25.46, 95% CI = 4.91-131.88), use of inhaled illicit drugs (OR = 3.56, 95% CI = 1.22-10.44), anal intercourse (OR = 3.93, 95% CI = 1.27-12.13), a sexual partner with a history of liver disease (OR = 5.45, 95% CI = 1.33-22.32), a sexual partner with a history of blood transfusions (OR = 4.79, 95% CI = 0.95-24.19), and sexual partner with a history of intravenous drug use (OR = 3.46, 95% CI = 1.24-9.65).