Genetic control of tumor development in malformation syndromes

One of the questions that arises frequently when caring for an individual with a malformation syndrome, is whether some form of tumor surveillance is indicated. In some syndromes there is a highly variable increased risk to develop tumors, while in others this is not the case. The risks can be hard...

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Bibliographic Details

Published in:	American journal of medical genetics. Part A Vol. 185; no. 2; pp. 324 - 335
Main Authors:	Postema, Floor A.M., Oosterwijk, Jan C., Hennekam, Raoul C.
Format:	Journal Article
Language:	English
Published:	Hoboken, USA John Wiley & Sons, Inc 01-02-2021 Wiley Subscription Services, Inc
Subjects:	cancer CNVs epigenetics genetic compensation Genetic control mosaicism tumor predisposition syndrome Tumors cancer genetic compensation tumor predisposition syndrome epigenetics CNVs mosaicism
Online Access:	Get full text
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