Prevention and Treatment of Oral Complications in Hematologic Childhood Cancer Patients: An Update

• Published in: Children (Basel) Vol. 9; no. 4; p. 566
• Main Authors: Ferrández-Pujante, Alba, Pérez-Silva, Amparo, Serna-Muñoz, Clara, Fuster-Soler, José Luis, Galera-Miñarro, Ana Mª, Cabello, Inmaculada, Ortiz-Ruiz, Antonio J
• Format: Journal Article
• Language: English
• Published: Switzerland MDPI AG 15-04-2022; MDPI
• Subjects: Age; Bone marrow; Cancer therapies; Catheters; Chemotherapy; dental management and oncology; Disease prevention; Hematology; Hospitals; Infections; Leukemia; Medical prognosis; Mucositis; Nervous system; Oncology; Oral cancer; oral care in paediatric oncologic patients; Oral hygiene; oral hygiene and oncology; oral prophylaxis and oncology; Patients; Pediatrics; Radiation therapy; Review; Transplants & implants; Tumors; Spain; oral hygiene and oncology; dental management and oncology; oral prophylaxis and oncology; oral care in paediatric oncologic patients
• ISSN: 2227-9067; 2227-9067
• DOI: 10.3390/children9040566

Cancers have a highly negative impact on the quality of life of paediatric patients and require an individualised oral treatment program for the phases of the disease. The aim of this study was to update existing research on oral care in children diagnosed with cancer. We carried out a literature search (in English, Spanish and Portuguese) in the Pubmed, Cochrane Library, EBSCO, WOS, SciELO, Lilacs, ProQuest, and SCOPUS databases and the websites of hospitals that treat childhood cancers. We found 114 articles and two hospital protocols. After review, we describe the interventions necessary to maintain oral health in children with cancer, divided into: phase I, before initiation of cancer treatment (review of medical record and oral history, planning of preventive strategies and dental treatments); phase II, from initiation of chemo-radiotherapy to 30-45 days post-therapy (maintenance of oral hygiene, reinforcement of parent/patient education in oral care, prevention and treatment of complications derived from cancer treatment); phase III, from 1 year to lifetime (periodic check-ups, maintenance, and reinforcement of oral hygiene, dental treatments, symptomatic care of the effects of long-term cancer treatment). The use of standardised protocols can avoid or minimise oral cancer complications and the side effects of cancer therapies.