SENSITIVE AND SIMPLE DETERMINATION OF VITAMIN K1 IN HUMAN PLASMA BY ULTRA-PERFORMANCE LIQUID CHROMATOGRAPHY COUPLED WITH A FLUORESCENCE DETECTOR

We developed a sensitive and simple method for the determination of vitamin K1 (VK1) in human plasma using ultra-performance liquid chromatography with post-column reduction. VK1 was extracted with single-step liquid-liquid partitioning. As an analytical column, we used an ACQUITY CSH C18 (1.7 µm, 2...

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Bibliographic Details

Published in:	Journal of liquid chromatography & related technologies Vol. 36; no. 8; pp. 1068 - 1077
Main Authors:	Ohno, Izumi, Araki, Takuya, Kawano, Masashi, Nakamura, Tomonori, Yamamoto, Koujirou
Format:	Journal Article
Language:	English
Published:	Abingdon Taylor & Francis Group 01-03-2013 Taylor & Francis Ltd
Subjects:	Detectors Fluorescence fluorescence detector Human Liquid chromatography liquid-liquid extraction Mathematical analysis Methyl alcohol MK-8 post-column reduction UPLC vitamin K1 Vitamins
Online Access:	Get full text
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