The Role of the Pancreatic Extracellular Matrix as a Tissue Engineering Support for the Bioartificial Pancreas

Type 1 diabetes mellitus (T1DM) is a chronic condition primarily managed with insulin replacement, leading to significant treatment costs. Complications include vasculopathy, cardiovascular diseases, nephropathy, neuropathy, and reticulopathy. Pancreatic islet transplantation is an option but its su...

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Bibliographic Details
Published in:	Biomimetics (Basel, Switzerland) Vol. 9; no. 10; p. 598
Main Authors:	Santos da Silva, Thamires, Silva-Júnior, Leandro Norberto da, Horvath-Pereira, Bianca de Oliveira, Valbão, Maria Carolina Miglino, Garcia, Matheus Henrique Herminio, Lopes, Juliana Barbosa, Reis, Carlos Henrique Bertoni, Barreto, Rodrigo da Silva Nunes, Buchaim, Daniela Vieira, Buchaim, Rogerio Leone, Miglino, Maria Angelica
Format:	Journal Article
Language:	English
Published:	Switzerland MDPI AG 02-10-2024 MDPI
Subjects:	Biological products Biomaterials Blood & organ donations Cardiovascular diseases Cell adhesion Cell differentiation Cell migration Cell viability Circulatory system decellularization Diabetes diabetes mellitus Diabetes mellitus (insulin dependent) Diabetes therapy Diabetic neuropathy Excretory system Extracellular matrix Glycoproteins Health aspects Immunosuppression Immunotherapy Insulin insulin-producing cells Islet cells Methods Nephropathy Neuropathy Pancreas Pancreas transplantation Pancreatic islet transplantation Public health Review Success Tissue engineering Transplantation of organs, tissues, etc Type 1 diabetes Type 2 diabetes Vascular diseases Vascularization Veins & arteries Brazil insulin-producing cells tissue engineering diabetes mellitus decellularization extracellular matrix
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