Alpha lipoic acid intoxication in an adolescent girl - Case report and review of the literature
Alpha-lipoic acid is a widely used medication that does not need a prescription. Although it is safely used in adults, hitherto no safe dose for children has been reported, and there is no known antidote. The medical literature provides four reports of alpha-lipoic acid intoxication in the pediatric...
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| Published in: | Turk Pediatri Arsivi Vol. 55; no. 3; pp. 328 - 330 |
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| Main Author: | |
| Format: | Journal Article |
| Language: | English |
| Published: |
Istanbul
Aves Yayincilik Ltd. STI
01-09-2020
Kare Publishing |
| Subjects: | |
| Online Access: | Get full text |
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| Summary: | Alpha-lipoic acid is a widely used medication that does not need a prescription. Although it is safely used in adults, hitherto no safe dose for children has been reported, and there is no known antidote. The medical literature provides four reports of alpha-lipoic acid intoxication in the pediatric population to date. This case-report is the lowest known dose of alpha-lipoic acid intake leading to poisoning in a teenager. |
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| Bibliography: | Alpha-lipoic acid is a widely used antioxidant and is also used for the treatment of many diseases such as diabetic neuropathies, autoimmune and neurodegenerative disease, hepatic disorders, and cancer. Although alpha-lipoic acid demonstrates a wide and safe therapeutic range in adults, there is no reported safety dosage in the pediatric population. The known about this topic Contribution of the study Alpha-lipoic acid intoxication is a very rare condition in the pediatric population, this is the fifth case reported in the pediatric literature. This patient developed a seizure and coagulopathy emerging with the lowest known dose of alpha-lipoic acid ingestion. |
| ISSN: | 1306-0015 2757-6256 1308-6278 |
| DOI: | 10.14744/TurkPediatriArs.2019.66564 |