MDR1/P-gp and VEGF Synergistically Enhance the Invasion of Hep-2 Cells with Multidrug Resistance Induced by Taxol

Background Tumor invasion/metastasis and multidrug resistance (MDR) are the main causes of treatment failure and high mortality in all kinds of cancer patients. The relationship between the two factors is still unclear. The aim of this study is to investigate the association between MDR and invasion...

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Bibliographic Details
Published in:	Annals of surgical oncology Vol. 16; no. 5; pp. 1421 - 1428
Main Authors:	Li, Li, Jiang, Alice C., Dong, Pin, Wang, Haibo, Xu, Wei, Xu, Chengzhi
Format:	Journal Article
Language:	English
Published:	New York Springer-Verlag 01-05-2009 Springer Nature B.V
Subjects:	Antineoplastic Agents, Phytogenic - pharmacology ATP Binding Cassette Transporter, Sub-Family B ATP-Binding Cassette, Sub-Family B, Member 1 - biosynthesis Cell Line, Tumor Drug Resistance, Multiple - drug effects Drug Resistance, Neoplasm - drug effects Humans Laryngeal Neoplasms - drug therapy Laryngeal Neoplasms - metabolism Medicine Medicine & Public Health Neoplasm Invasiveness Oncology Original Article-Translational Research and Biomarkers Paclitaxel - pharmacology Surgery Surgical Oncology Vascular Endothelial Growth Factor Receptor-2 - biosynthesis Vascular Endothelial Growth Factor Invasive Ability Taxol MDR1 Expression Express Vascular Endothelial Growth Factor Receptor
Online Access:	Get full text
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