Prolonged partial obstruction during sleep is a NREM phenomenon

• Published in: Respiratory physiology & neurobiology Vol. 255; pp. 43 - 49
• Main Authors: Himanen, Sari-Leena, Martikkala, Lauri, Sulkamo, Saramia, Rutanen, Antti, Huupponen, Eero, Tenhunen, Mirja, Saunamäki, Tiia
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier B.V 01-09-2018
• Subjects: Breathing effort; Emfit; Flow limitation; OSA; Partial obstruction; Sleep EEG; Sleep-disordered breathing; Emfit; Breathing effort; Partial obstruction; Sleep EEG; Flow limitation; OSA; Sleep-disordered breathing
• ISSN: 1569-9048; 1878-1519
• DOI: 10.1016/j.resp.2018.05.009

•Prolonged partial obstruction causes no decrease in the amount of deep sleep.•Prolonged partial obstruction during sleep emergences in N2 and N3.•Sleep disordered breathing does not always ameliorate in deep sleep but changes the type.
Prolonged partial obstruction (PPO) is a common finding in sleep studies. Although not verified, it seems to emerge in deep sleep. We study the effect of PPO on sleep architecture or sleep electroencephalography (EEG) frequency.
Fifteen OSA patients, 15 PPO + OSA patients and 15 healthy subjects underwent a polysomnography. PPO was detected from Emfit mattress signal. Visual sleep parameters and median NREM sleep frequency of the EEG channels were evaluated.
The amount of deep sleep (N3) did not differ between the PPO + OSA and control groups (medians 11.8% and 13.8%). PPO + OSA-patients’ N3 consisted mostly of PPO. PPO + OSA patients had lighter sleep than healthy controls in three brain areas (Fp2-A1, C4-A1, O1-A2, p-values < 0.05).
PPO evolved in NREM sleep and especially in N3 indicating that upper airway obstruction does not always ameliorate in deep sleep but changes the type. Even if PPO + OSA-patients had N3, their NREM sleep was lighter in three EEG locations. This might reflect impaired recovery function of sleep.