Developmental Toxicology Evaluations—Issues with Including Neurotoxicology and Immunotoxicology Assessments in Reproductive Toxicology Studies

Developmental and reproductive toxicology (DART) has routinely been a part of safety assessment. Attention is now focused on the effects of chemicals on the developing nervous and immune systems. This focus on developmental neurotoxicology (DNT) and developmental immunotoxicology (DIT) is based on t...

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Bibliographic Details
Published in:	Toxicological sciences Vol. 88; no. 1; pp. 24 - 29
Main Authors:	Ladics, Gregory S., Chapin, Robert E., Hastings, Kenneth L., Holsapple, Michael P., Makris, Susan L., Sheets, Larry P., Woolhiser, Michael R., Burns-Naas, Leigh Ann
Format:	Journal Article
Language:	English
Published:	United States Oxford University Press 01-11-2005
Subjects:	Abnormalities, Drug-Induced Animals combination study DART developmental and reproductive toxicology developmental immunotoxicology developmental neurotoxicology DIT DNT Female hazard identification Immune System - drug effects Immune System - embryology Male Mice Nervous System - drug effects Nervous System - embryology panel discussion Rats Reproduction - drug effects study design Teratogens - classification Teratogens - toxicity Xenobiotics - classification Xenobiotics - toxicity
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