$A different insight in hair analysis: Simultaneous measurement of antipsychotic drugs and metabolites in the protein and melanin fraction of hair from criminal justice patients$
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A different insight in hair analysis: Simultaneous measurement of antipsychotic drugs and metabolites in the protein and melanin fraction of hair from criminal justice patients

•Validation an UPLC-MS/MS method for the analysis of 19 antipsychotics in hair.•Separated drug concentration measurements in the melanin and the protein fraction.•Evaluation of patient medication adherence with hair analysis. Previous studies have postulated that four structural compartments may be...

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Bibliographic Details
Published in:	Forensic science international Vol. 312; p. 110337
Main Authors:	Ramírez Fernández, María del Mar, Baumgartner, Werner A., Wille, Sarah M.R., Farabee, David, Samyn, Nele, Baumgartner, Annette M.
Format:	Journal Article
Language:	English
Published:	Ireland Elsevier B.V 01-07-2020 Elsevier Limited
Subjects:	Affinity Antipsychotic Agents - analysis Antipsychotics Aripiprazole Ball milling Binding Blood Cartridges Cation exchange Cation exchanging Centrifugation Chlorpromazine Chromatography, High Pressure Liquid - methods Clozapine Color Coloring Agents Crime Damage Decontamination Dimethyl sulfoxide Dithiothreitol Drug development Drug use Drugs Evaluation Forensic sciences Forensic Toxicology - methods Hair Hair - chemistry Hair analysis Haloperidol Humans Imprisonment Judicial system Melanin Melanins - chemistry Metabolites Methods Methylene Blue Olanzapine Patient compliance Prisoners Protein Protein folding Proteins Proteins - chemistry Psychotropic drugs Quetiapine Risperidone Scalp Solid phases Substance Abuse Detection - methods Tandem Mass Spectrometry - methods UPLC–MS/MS Belgium France Hair Antipsychotics Olanzapine Haloperidol Risperidone UPLC–MS/MS Chlorpromazine Protein Melanin Quetiapine
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