An evaluation of the cut-off value of methamphetamine in hair samples via HPLC-MS/MS

•The analytic method of MAMP and AMP in hair was optimized.•LOD and LOQ for MAMP under the established analytic method were 0.004 and 0.01ng/mg respectively.•Based on the data from 563 MAMP Chinese users, the cut-off value is proposed to be 0.97ng/mg.•The cut-off value is optimized by ROC and AMP de...

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Bibliographic Details
Published in:	Forensic science international Vol. 306; p. 110094
Main Authors:	Ou, Jun, Zhang, Yingyi, Chen, Shenshu, Zhong, Chaoqun, Xu, Qilin, Xu, Daihua, Yan, Xiaoli
Format:	Journal Article
Language:	English
Published:	Ireland Elsevier B.V 01-01-2020 Elsevier Limited
Subjects:	Alcohol Amphetamine Amphetamines Analysis Asian Continental Ancestry Group Caustic soda Central Nervous System Stimulants - analysis China Chromatography, High Pressure Liquid Cut-off Drug abuse Drug misuse Drug testing Forensic sciences Forensic Toxicology Hair Hair - chemistry Hair analysis High-performance liquid chromatography HPLC-MS/MS Humans Limit of Detection Liquid chromatography Mass Spectrometry Mathematical analysis Methamphetamine Methamphetamine - analysis Methods Quality control Quality standards Substance Abuse Detection - methods Substance-Related Disorders - diagnosis China Hair HPLC-MS/MS Amphetamine Cut-off Analysis Methamphetamine Drug misuse
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