Vicarious nucleophilic substitution of hydrogen vs. ANRORC-type ring transformation in reactions of 1,2,4-triazines with α-halocarbanions. Novel route to functionalized pyrazoles

• Published in: ARKIVOC Vol. 2004; no. 3; pp. 74 - 84
• Main Authors: Rykowski, Andrzej, Wolinska, Ewa, Branowska, Danuta, Plas, Henk C. Van der
• Format: Journal Article Web Resource
• Language: English
• Published: Ann Arbor, MI: Michigan Publishing, University of Michigan Library 01-01-2004; Ann Arbor, Michigan: Michigan Publishing, University of Michigan Library; Arkat USA, Inc
• Subjects: nitroarenes; organic-anions; sulfones
• ISSN: 1551-7012; 1551-7004; 1551-7012
• DOI: 10.3998/ark.5550190.0005.308

A novel route to pyrazole derivatives bearing sulfonyl, aminosulfonyl, alkoxy- and aryloxysulfonyl groups at C-3 by ring transformation of 3-chloro-6-aryl-1,2,4-triazines 1a-c with alpha-halocarbanions 2a-h is described.