Effect of Plate Configuration in the Primary Stability of Osteotomies and Biological Reconstructions of Femoral Defects: Finite-Element Study

• Published in: Bioengineering (Basel) Vol. 11; no. 5; p. 416
• Main Authors: Neto, M A, Paulino, M F, Amaro, A M
• Format: Journal Article
• Language: English
• Published: Switzerland MDPI AG 01-05-2024
• Subjects: allograft; Allografts; Aluminum; Analysis; biological reconstruction; Biomechanics; Bone grafts; Bone surgery; Bone tumors; Bone-grafting; Bones; Complications and side effects; Compression; Compression loads; Configurations; Diaphysis; Environment models; Femur; Finite element method; finite-element analysis; Fixation; Fractures; Graft rejection; Head movement; Mathematical models; Mechanical loading; Nonlinear analysis; Osteosynthesis; osteosynthesis plates; Osteotomy; Patient outcomes; Patient satisfaction; Plates; Prevention; Reconstructive surgery; Risk factors; stability; Statistical analysis; Systems stability; Tightening; Portugal; United States > US; biological reconstruction; osteosynthesis plates; finite-element analysis; allograft; stability
• ISSN: 2306-5354; 2306-5354
• DOI: 10.3390/bioengineering11050416

Osteosynthesis is an alternative treatment for stabilizing femur-bone traumas. The initial stability of the fixation systems is one of the biomechanical parameters affecting implant failure and bone union, especially in surgeries of intercalary reconstructions after the removal of bone tumors. This study aimed to investigate the initial biomechanical effect of using one or two osteosynthesis plate configurations for femoral fixation and the effect of fastening the allograft to the osteosynthesis plate in the case of femoral allograft reconstructions.
Three finite-element models of a femur with three different fixation conditions for a transverse osteotomy in the middle of the diaphysis, i.e., using one and two osteosynthesis plates and an intercalary allograft, were constructed. An eight-hole compression plate and a six-hole second plate were used to simulate osteosynthesis plates. The plate screws were tightened previously to the loading, and the tightening sequences simulate the bolt-tightening procedure in a surgical environment. The models were imported into the ADINA System for nonlinear analysis, using compression loads applied over the femur head.
Models with the dual fixation systems had the most outstanding compression stiffness. The femur head movement in the dual plate system was 24.8% smaller than in the single plate system. A statistical analysis of a region of interest (VOI) placed in the femur diaphysis showed that the biomechanical effect of using the dual plate system is smaller in the osteotomy region than at the femur head, e.g., a displacement average decrease of only 5% between the two systems, while the maximum value decreases by 26.8%. The allograft fixation to the second osteosynthesis plate leads to an improvement in the system stability.
The results presented in this work show that including the bolt analysis in the femoral diaphysis osteotomy fixation will allow for capturing the nonlinear behavior of the osteotomy region more realistically. The stability of the intercalary reconstruction of the femoral diaphysis was higher when the allograft was fastened to the second osteosynthesis plate.