Lack of Association Between a Common Polymorphism Near the INSIG2 Gene and BMI, Myocardial Infarction, and Cardiovascular Risk Factors

Epidemiological studies revealed an increasing prevalence of and a steep increase in obesity, a risk factor for cardiovascular disease. Because significant influence of a polymorphism, rs7566605, near the INSIG2 gene on BMI has been shown in the general population and in obesity cohorts, we hypothes...

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Bibliographic Details
Published in:	Obesity (Silver Spring, Md.) Vol. 17; no. 7; pp. 1390 - 1395
Main Authors:	Wiedmann, Silke, Neureuther, Katharina, Stark, Klaus, Reinhard, Wibke, Kallmünzer, Bernd, Baessler, Andrea, Fischer, Marcus, Linsel‐Nitschke, Patrick, Erdmann, Jeanette, Schunkert, Heribert, Hengstenberg, Christian
Format:	Journal Article
Language:	English
Published:	Oxford, UK Blackwell Publishing Ltd 01-07-2009
Subjects:	Adult Aged Aged, 80 and over Blood pressure Body Mass Index Cardiovascular disease Cardiovascular Diseases - epidemiology Cardiovascular Diseases - genetics Case-Control Studies Cholesterol Coronary vessels Diabetes Female Genetic Predisposition to Disease - genetics Genotype Heart attacks Humans Intracellular Signaling Peptides and Proteins - genetics Lipoproteins Male Membrane Proteins - genetics Metabolic syndrome Middle Aged Myocardial Infarction - epidemiology Myocardial Infarction - genetics Obesity Polymorphism Polymorphism, Single Nucleotide - genetics Risk Factors Vein & artery diseases Germany
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