Collagen IV of basement membranes: III. Chloride pressure is a primordial innovation that drives and maintains the assembly of scaffolds

Collagen IV scaffold is a primordial innovation enabling the assembly of a fundamental architectural unit of epithelial tissues-a basement membrane attached to polarized cells. A family of six α-chains (α1 to α6) coassemble into three distinct protomers that form supramolecular scaffolds, noted as c...

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Bibliographic Details
Published in:	The Journal of biological chemistry Vol. 299; no. 11; p. 105318
Main Authors:	Boudko, Sergei P, Pedchenko, Vadim K, Pokidysheva, Elena N, Budko, Alena M, Baugh, Rachel, Coates, Patrick Toby, Fidler, Aaron L, Hudson, Heather M, Ivanov, Sergey V, Luer, Carl, Pedchenko, Tetyana, Preston, Robert L, Rafi, Mohamed, Vanacore, Roberto, Bhave, Gautam, Hudson, Julie K, Hudson, Billy G
Format:	Journal Article
Language:	English
Published:	United States 01-11-2023
Subjects:	Animals Basement Membrane Chlorides Collagen Type IV - chemistry Mammals Mice Protein Structure, Tertiary Protein Subunits - analysis small molecule basement membrane protein evolution NC1 domain chloride phylogeny collagen IV protein self-assembly protein stability extracellular matrix
Online Access:	Get full text
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