Development of a novel antiadhesive material, alginate flakes, ex vivo and in vivo

Purpose Postoperative intra-abdominal adhesion sometimes causes significant morbidity. The aim of this study was to compare the efficacy of our newly developed antiadhesive material, alginate flakes, to the most commonly used combination of hyaluronic acid and carboxymethyl cellulose film. Methods S...

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Bibliographic Details
Published in:	Surgery today (Tokyo, Japan) Vol. 41; no. 7; pp. 970 - 977
Main Authors:	Hirasaki, Yoshinori, Fukunaga, Masaki, Kidokoro, Akio, Hashimoto, Ayumi, Nakamura, Tatsuo, Tsujimoto, Hiroyuki, Hagiwara, Akeo
Format:	Journal Article
Language:	English
Published:	Japan Springer Japan 01-07-2011
Subjects:	Alginates - administration & dosage Alginates - therapeutic use Animals Biocompatible Materials - administration & dosage Biocompatible Materials - therapeutic use Carboxymethylcellulose Sodium - administration & dosage Carboxymethylcellulose Sodium - therapeutic use Dermatologic Surgical Procedures Female Glucuronic Acid - administration & dosage Glucuronic Acid - therapeutic use Hexuronic Acids - administration & dosage Hexuronic Acids - therapeutic use Hyaluronic Acid - administration & dosage Hyaluronic Acid - therapeutic use Laparoscopy - adverse effects Medicine Medicine & Public Health Models, Animal Original Article Postoperative Complications - prevention & control Rats Rats, Wistar Surgery Surgical Oncology Swine Laparoscopic surgery Alginate Antiadhesive material Rat Prevention of adhesion
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