Antenatal steroids decrease blood-brain barrier permeability in the ovine fetus

Antenatal corticosteroid therapy reduces the incidence of intraventricular hemorrhage in premature infants. Enhanced microvascular integrity might provide protection against intraventricular hemorrhage. In the adult, there is evidence to suggest that the blood-brain barrier may be under hormonal con...

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Bibliographic Details
Published in:	The American journal of physiology Vol. 276; no. 2; pp. R283 - R289
Main Authors:	Stonestreet, B S, Petersson, K H, Sadowska, G B, Pettigrew, K D, Patlak, C S
Format:	Journal Article
Language:	English
Published:	United States 01-02-1999
Subjects:	Adrenal Cortex Hormones - pharmacology Aminoisobutyric Acids - antagonists & inhibitors Aminoisobutyric Acids - blood Aminoisobutyric Acids - metabolism Aminoisobutyric Acids - pharmacokinetics Animals Blood-Brain Barrier - drug effects Brain - embryology Brain - metabolism Capillary Permeability - drug effects Dexamethasone - pharmacology Fetus - metabolism Fetus - physiology Glucocorticoids - pharmacology Sheep - embryology Tissue Distribution
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