Are high-sensitivity troponins always reliable? Donor-recipient troponin transfusion in liver transplantation

Blood troponins are used to diagnose perioperative myocardial injury and infarction. During liver transplantation, a passive donor-recipient troponin transfer with the graft may result in an increase of troponins in the transplant recipient questioning the diagnosis of myocardial injury. We present...

Full description

Saved in:

Bibliographic Details
Published in:	British journal of anaesthesia : BJA Vol. 121; no. 6; p. 1212
Main Authors:	Vilchez-Monge, A L, Garutti, I, Lisbona, C J, Olmedilla, L, Perez-Peña, J M
Format:	Journal Article
Language:	English
Published:	England 01-12-2018
Subjects:	Adult Electrocardiography Humans Liver Transplantation - methods Male Middle Aged Tissue Donors Troponin - administration & dosage Troponin T - blood high-sensitivity troponin T diagnostic accuracy biomarker perioperative myocardial injury false positive myocardial infarction
Online Access:	Get more information
Tags:	Add Tag No Tags, Be the first to tag this record!

Description
Summary:	Blood troponins are used to diagnose perioperative myocardial injury and infarction. During liver transplantation, a passive donor-recipient troponin transfer with the graft may result in an increase of troponins in the transplant recipient questioning the diagnosis of myocardial injury. We present a case of liver transplantation with sudden elevation of recipient's serum troponin levels immediately after graft reperfusion and its subsequent normalization in which myocardial damage and other non-ischaemic potential causes were ruled out. Patient consent for publication was obtained prior to submission of the manuscript.
ISSN:	1471-6771
DOI:	10.1016/j.bja.2018.08.024