Impact of the post-weaning parasitism history on an experimental Haemonchus contortus infection in Creole goat kids

• Published in: Veterinary parasitology Vol. 207; no. 1-2; pp. 166 - 169
• Main Authors: Ceï, W., Mahieu, M., Philibert, L., Arquet, R., Alexandre, G., Mandonnet, N., Bambou, J.C.
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier B.V 15-01-2015; Elsevier
• Subjects: Animals; Breeding; Cattle; Feces - parasitology; Female; Gastrointestinal Diseases - immunology; Gastrointestinal Diseases - parasitology; Gastrointestinal Diseases - veterinary; Genetic resistance; Goat Diseases - parasitology; Goat kids; Goats; Haemonchiasis - immunology; Haemonchiasis - parasitology; Haemonchiasis - veterinary; Haemonchus - immunology; Haemonchus - isolation & purification; Haemonchus contortus; Immunity; Life Sciences; Parasite Egg Count - veterinary; Weaning; Haemonchus contortus; Goat kids; Immunity; Genetic resistance
• ISSN: 0304-4017; 1873-2550
• DOI: 10.1016/j.vetpar.2014.11.010

•We studied the response to an experimental parasitic infection in kids differing in the parasitism history.•We evaluated the interaction between the post-weaning parasitism level and the kid's genetic status.•A protection against an experimental infection occurred during the post-weaning period.•No interaction was observed between this level of protection and the genetic status.
Gastrointestinal nematode (GIN) infections have an important negative impact on small ruminant production. The selection of genotypes resistant to these parasitic infections is a promising alternative control strategy. Thus, resistance against GIN is an important component of small ruminant breeding schemes, based on phenotypic measurements of resistance in immune mature infected animals. In this study we evaluated both the impact of the post-weaning parasitism history on the response to an experimental Haemonchus contortus infection of resistant and susceptible Creole kids chosen on the basis of their estimated breeding value, and the interaction with the kid's genetic status. During the post-weaning period (from 3 months until 7 months of age) Creole kids were reared at pasture according to four different levels of a mixed rotational stocking system with Creole cattle: 100% (control), 75% (GG75), 50% (GG50), and 25% (GG25) of the total stocking rate of the pasture. The level of infection of the kids decreased significantly at 50% and 25% of the total stocking rate. After the post-weaning period at pasture, at 11 months of age kids were experimentally infected with H. contortus. The faecal egg counts (FEC) were significantly lower in the groups showing the highest FEC at pasture. This result suggests that a degree of protection against an experimental H. contortus infection occurred during the post-weaning period and was dependant on the level of parasitism. Interestingly, no interaction was observed between this level of protection and the genetic status. In conclusion, the level of post-weaning natural parasitism history at pasture would not influence the genetic status evaluation. More generally our results suggest that it would be better to expose kids to a high level of gastrointestinal parasitism during the post-weaning period in order to increase the basal level of resistance thereafter.