Correlation between gray matter volume in the temporal lobe and depressive symptoms in patients with Alzheimer's disease

Depressive symptoms may be associated with the volume changes of frontal and temporal lobe in patients with Alzheimer's disease. •Depression might be an aggravating factor in Alzheimer's disease.•Left inferior temporal volume was decreased in AD patients with depression.•Depressive symptom...

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Bibliographic Details
Published in:	Neuroscience letters Vol. 548; pp. 15 - 20
Main Authors:	Son, Ji Hyun, Han, Doug Hyun, Min, Kyung Joon, Kee, Baik Seok
Format:	Journal Article
Language:	English
Published:	Ireland Elsevier Ireland Ltd 26-08-2013
Subjects:	Aged Aged, 80 and over Alzheimer Disease - complications Alzheimer Disease - diagnosis Alzheimer's disease (AD) Consortium to Establish a Registry for Alzheimer's disease (CERAD) Depression - complications Depression - diagnosis Female Frontal Lobe - pathology Geriatric Depression Scale (GDS) Humans Imaging, Three-Dimensional - methods Magnetic Resonance Imaging - methods Male Middle Aged Neurons - pathology Organ Size Reproducibility of Results Sensitivity and Specificity Temporal Lobe - pathology Voxel based morphometry (VBM) Consortium to Establish a Registry for Alzheimer's disease (CERAD) Alzheimer's disease (AD) Geriatric Depression Scale (GDS) Voxel based morphometry (VBM)
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