Drug-Induced Hypersensivity Syndrome Associated with Epstein-Barr Virus Infection: A Pediatric Case Report

• Published in: Pediatric dermatology Vol. 26; no. 2; pp. 229 - 231
• Main Authors: SCAGNI, PAOLA, MORELLO, MAURA, RAMUS, MARISA VIETTI, AGOSTINI, MANUELA, PAGLIERO, ROSAURA
• Format: Journal Article
• Language: English
• Published: Oxford, UK Blackwell Publishing Ltd 01-03-2009; Wiley
• Subjects: Anticonvulsants - adverse effects; Biological and medical sciences; Carbamazepine - adverse effects; Child; Dermatology; Drug Hypersensitivity - etiology; Epstein-Barr virus; Epstein-Barr Virus Infections - diagnosis; Exanthema - chemically induced; Fever - chemically induced; General aspects; Hepatomegaly - chemically induced; Human viral diseases; Humans; Infectious diseases; Lymphatic Diseases - chemically induced; Male; Medical sciences; Viral diseases; Viral diseases of the respiratory system and ent viral diseases; Human; Infection; Virus; Case study; Associated virus; Pediatrics; Dermatology; Viral disease; Child; Infectious mononucleosis
• ISSN: 0736-8046; 1525-1470
• DOI: 10.1111/j.1525-1470.2009.00891.x

:  Drug hypersensitivity syndrome is an acute, severe, multi‐organ systemic reaction, usually developing with aromatic antiepileptic drugs. Interaction between drug‐induced hypersensivity syndrome and viral infections is debated. We report the first case of severe carbamazepine‐induced hypersensivity syndrome associated with Epstein‐Barr virus infection in a child.