fmr1 Mutation Alters the Early Development of Sensory Coding and Hunting and Social Behaviors in Larval Zebrafish

Autism spectrum disorders (ASDs) are developmental in origin; however, little is known about how they affect the early development of behavior and sensory coding. The most common inherited form of autism is Fragile X syndrome (FXS), caused by a mutation in Mutation of in zebrafish causes anxiety-lik...

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Bibliographic Details
Published in:	The Journal of neuroscience Vol. 43; no. 7; pp. 1211 - 1224
Main Authors:	Zhu, Shuyu I, McCullough, Michael H, Pujic, Zac, Sibberas, Jordan, Sun, Biao, Darveniza, Thomas, Bucknall, Bianca, Avitan, Lilach, Goodhill, Geoffrey J
Format:	Journal Article
Language:	English
Published:	United States Society for Neuroscience 15-02-2023
Subjects:	Animals Anxiety Autism Behavior Coding Danio rerio Disease Models, Animal Excitability FMR1 protein Fragile X Mental Retardation Protein - genetics Fragile X syndrome Fragile X Syndrome - genetics Genotypes Hunting Hyperactivity Hypersensitivity Information processing Intellectual disabilities Larva - metabolism Larvae Mice Mice, Knockout Mutation Mutation - genetics Predatory behavior Prey RNA-Binding Proteins - genetics Sensory integration Sensory stimulation Social Behavior Social factors Tectum Vertebrates Visual stimuli Zebrafish Zebrafish - metabolism Zebrafish Proteins - genetics Zebrafish Proteins - metabolism environmental enrichment optic tectum behavior neural assemblies
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