The Pathology of Diphtheria

Diphtheria is an acute, communicable disease caused by Corynebacterium diphtheriae. The disease is generally characterized by local growth of the bacterium in the pharynx with pseudomembrane formation or, less commonly, in the stomach or lungs; systemic dissemination of toxin then invokes lesions in...

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Published in:The Journal of infectious diseases Vol. 181; no. Supplement-1; pp. S116 - S120
Main Authors: Hadfield, Ted L., McEvoy, Peter, Polotsky, Yury, Tzinserling, Vsevolod A., Yakovlev, Alexey A.
Format: Journal Article
Language:English
Published: United States The University of Chicago Press 01-02-2000
University of Chicago Press
Oxford University Press
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Abstract Diphtheria is an acute, communicable disease caused by Corynebacterium diphtheriae. The disease is generally characterized by local growth of the bacterium in the pharynx with pseudomembrane formation or, less commonly, in the stomach or lungs; systemic dissemination of toxin then invokes lesions in distant organs. Acute disease of the upper respiratory tract usually involves one or more of the following: tonsillar zones, larynx, soft palate, uvula, and nasal cavities. A recent epidemic in Russia emphasized the role of vaccination in reducing disease in children and adults.
AbstractList Diphtheria is an acute, communicable disease caused by Corynebacterium diphtheriae. The disease is generally characterized by local growth of the bacterium in the pharynx with pseudomembrane formation or, less commonly, in the stomach or lungs; systemic dissemination of toxin then invokes lesions in distant organs. Acute disease of the upper respiratory tract usually involves one or more of the following: tonsillar zones, larynx, soft palate, uvula, and nasal cavities. A recent epidemic in Russia emphasized the role of vaccination in reducing disease in children and adults.
Author Tzinserling, Vsevolod A.
Yakovlev, Alexey A.
Hadfield, Ted L.
Polotsky, Yury
McEvoy, Peter
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  givenname: Peter
  surname: McEvoy
  fullname: McEvoy, Peter
  organization: Armed Forces Institute of Pathology, Washington, DC
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  surname: Polotsky
  fullname: Polotsky, Yury
  organization: Walter Reed Army Institute of Research, Washington, DC
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  givenname: Vsevolod A.
  surname: Tzinserling
  fullname: Tzinserling, Vsevolod A.
  organization: St. Petersburg Pediatric Medical Institute, St. Petersburg, Russia
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  givenname: Alexey A.
  surname: Yakovlev
  fullname: Yakovlev, Alexey A.
  organization: St. Petersburg Pediatric Medical Institute, St. Petersburg, Russia
BackLink https://www.ncbi.nlm.nih.gov/pubmed/10657202$$D View this record in MEDLINE/PubMed
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Snippet Diphtheria is an acute, communicable disease caused by Corynebacterium diphtheriae. The disease is generally characterized by local growth of the bacterium in...
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SubjectTerms Adult
Child
Corynebacterium diphtheriae
Corynebacterium diphtheriae - isolation & purification
Diphtheria
Diphtheria - epidemiology
Diphtheria - microbiology
Diphtheria - pathology
Disease Outbreaks
Epidemiology
Humans
Infections
Infectious diseases
Lesions
Myocardium
Necrosis
Pathology
Toxins
USSR - epidemiology
Title The Pathology of Diphtheria
URI https://api.istex.fr/ark:/67375/HXZ-B68962FL-5/fulltext.pdf
https://www.jstor.org/stable/30109984
https://www.ncbi.nlm.nih.gov/pubmed/10657202
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https://search.proquest.com/docview/70896322
Volume 181
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