The Pathology of Diphtheria
Diphtheria is an acute, communicable disease caused by Corynebacterium diphtheriae. The disease is generally characterized by local growth of the bacterium in the pharynx with pseudomembrane formation or, less commonly, in the stomach or lungs; systemic dissemination of toxin then invokes lesions in...
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Published in: | The Journal of infectious diseases Vol. 181; no. Supplement-1; pp. S116 - S120 |
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The University of Chicago Press
01-02-2000
University of Chicago Press Oxford University Press |
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Abstract | Diphtheria is an acute, communicable disease caused by Corynebacterium diphtheriae. The disease is generally characterized by local growth of the bacterium in the pharynx with pseudomembrane formation or, less commonly, in the stomach or lungs; systemic dissemination of toxin then invokes lesions in distant organs. Acute disease of the upper respiratory tract usually involves one or more of the following: tonsillar zones, larynx, soft palate, uvula, and nasal cavities. A recent epidemic in Russia emphasized the role of vaccination in reducing disease in children and adults. |
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AbstractList | Diphtheria is an acute, communicable disease caused by Corynebacterium diphtheriae. The disease is generally characterized by local growth of the bacterium in the pharynx with pseudomembrane formation or, less commonly, in the stomach or lungs; systemic dissemination of toxin then invokes lesions in distant organs. Acute disease of the upper respiratory tract usually involves one or more of the following: tonsillar zones, larynx, soft palate, uvula, and nasal cavities. A recent epidemic in Russia emphasized the role of vaccination in reducing disease in children and adults. |
Author | Tzinserling, Vsevolod A. Yakovlev, Alexey A. Hadfield, Ted L. Polotsky, Yury McEvoy, Peter |
Author_xml | – sequence: 1 givenname: Ted L. surname: Hadfield fullname: Hadfield, Ted L. email: hadfield@afip.osd.mil organization: Armed Forces Institute of Pathology, Washington, DC – sequence: 2 givenname: Peter surname: McEvoy fullname: McEvoy, Peter organization: Armed Forces Institute of Pathology, Washington, DC – sequence: 3 givenname: Yury surname: Polotsky fullname: Polotsky, Yury organization: Walter Reed Army Institute of Research, Washington, DC – sequence: 4 givenname: Vsevolod A. surname: Tzinserling fullname: Tzinserling, Vsevolod A. organization: St. Petersburg Pediatric Medical Institute, St. Petersburg, Russia – sequence: 5 givenname: Alexey A. surname: Yakovlev fullname: Yakovlev, Alexey A. organization: St. Petersburg Pediatric Medical Institute, St. Petersburg, Russia |
BackLink | https://www.ncbi.nlm.nih.gov/pubmed/10657202$$D View this record in MEDLINE/PubMed |
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SubjectTerms | Adult Child Corynebacterium diphtheriae Corynebacterium diphtheriae - isolation & purification Diphtheria Diphtheria - epidemiology Diphtheria - microbiology Diphtheria - pathology Disease Outbreaks Epidemiology Humans Infections Infectious diseases Lesions Myocardium Necrosis Pathology Toxins USSR - epidemiology |
Title | The Pathology of Diphtheria |
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