Evidence for qnrB1 and aac(6′)-Ib-cr in CTX-M-15–producing uropathogenic Enterobacteriaceae in an Italian teaching hospital

Abstract In this work, we report the spread of CTX-M–producing uropathogenic ciprofloxacin-resistant Enterobacteriaceae. This is the first identification in Italy of the simultaneous presence of aac(6′)-Ib-cr , qnrB1 , and blaCTX-M-15 resistance determinants in an Escherichia coli strain isolated fr...

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Published in:	Diagnostic microbiology and infectious disease Vol. 64; no. 1; pp. 90 - 93
Main Authors:	Perilli, Mariagrazia, Forcella, Chiara, Celenza, Giuseppe, Frascaria, Patrizia, Segatore, Bernardetta, Pellegrini, Cristina, Amicosante, Gianfranco
Format:	Journal Article
Language:	English
Published:	United States Elsevier Inc 01-05-2009
Subjects:	aac(6')-Ib-cr Aminoglycosides - pharmacology Anti-Bacterial Agents - pharmacology beta-Lactamases - biosynthesis beta-Lactams - pharmacology Ciprofloxacin - pharmacology Drug Resistance, Multiple, Bacterial Enterobacteriaceae Enterobacteriaceae - drug effects Enterobacteriaceae - isolation & purification Enterobacteriaceae Infections - microbiology Escherichia coli Gene Order Genes, Bacterial Hospitals, Teaching Humans Infectious Disease Integrons Internal Medicine Italy qnr Resistance Urinary Tract Infections - microbiology Italy Resistance Integrons aac(6')-Ib-cr qnr
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Abstract	Abstract In this work, we report the spread of CTX-M–producing uropathogenic ciprofloxacin-resistant Enterobacteriaceae. This is the first identification in Italy of the simultaneous presence of aac(6′)-Ib-cr , qnrB1 , and blaCTX-M-15 resistance determinants in an Escherichia coli strain isolated from urine of a nonhospitalized patient.
AbstractList	In this work, we report the spread of CTX-M-producing uropathogenic ciprofloxacin-resistant Enterobacteriaceae. This is the first identification in Italy of the simultaneous presence of aac(6')-Ib-cr, qnrB1, and bla(CTX-M-15) resistance determinants in an Escherichia coli strain isolated from urine of a nonhospitalized patient. In this work, we report the spread of CTX-M-producing uropathogenic ciprofloxacin-resistant Enterobacteriaceae. This is the first identification in Italy of the simultaneous presence of aac(6')-Ib-cr, qnrB1, and bla sub(C) sub(T) sub(X) sub(-) sub(M) sub(-) sub(1) sub(5) resistance determinants in an Escherichia coli strain isolated from urine of a nonhospitalized patient. In this work, we report the spread of CTX-M–producing uropathogenic ciprofloxacin-resistant Enterobacteriaceae. This is the first identification in Italy of the simultaneous presence of aac(6′)-Ib-cr, qnrB1, and bla CTX-M-15 resistance determinants in an Escherichia coli strain isolated from urine of a nonhospitalized patient. Abstract In this work, we report the spread of CTX-M–producing uropathogenic ciprofloxacin-resistant Enterobacteriaceae. This is the first identification in Italy of the simultaneous presence of aac(6′)-Ib-cr , qnrB1 , and blaCTX-M-15 resistance determinants in an Escherichia coli strain isolated from urine of a nonhospitalized patient.
Author	Perilli, Mariagrazia Celenza, Giuseppe Amicosante, Gianfranco Pellegrini, Cristina Forcella, Chiara Frascaria, Patrizia Segatore, Bernardetta
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Cites_doi	10.1128/AAC.00444-07 10.4067/S0034-98872004001000003 10.1086/313719 10.1128/JCM.41.9.4264-4269.2003 10.1128/CMR.18.4.657-686.2005 10.1038/nm1347 10.1128/JCM.33.9.2233-2239.1995 10.1128/AAC.00068-06 10.1128/AAC.48.1.1-14.2004
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Snippet	Abstract In this work, we report the spread of CTX-M–producing uropathogenic ciprofloxacin-resistant Enterobacteriaceae. This is the first identification in... In this work, we report the spread of CTX-M–producing uropathogenic ciprofloxacin-resistant Enterobacteriaceae. This is the first identification in Italy of... In this work, we report the spread of CTX-M-producing uropathogenic ciprofloxacin-resistant Enterobacteriaceae. This is the first identification in Italy of...
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SubjectTerms	aac(6')-Ib-cr Aminoglycosides - pharmacology Anti-Bacterial Agents - pharmacology beta-Lactamases - biosynthesis beta-Lactams - pharmacology Ciprofloxacin - pharmacology Drug Resistance, Multiple, Bacterial Enterobacteriaceae Enterobacteriaceae - drug effects Enterobacteriaceae - isolation & purification Enterobacteriaceae Infections - microbiology Escherichia coli Gene Order Genes, Bacterial Hospitals, Teaching Humans Infectious Disease Integrons Internal Medicine Italy qnr Resistance Urinary Tract Infections - microbiology
Title	Evidence for qnrB1 and aac(6′)-Ib-cr in CTX-M-15–producing uropathogenic Enterobacteriaceae in an Italian teaching hospital
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