Functional evidence of post-transcriptional regulation by pseudogenes

Pseudogenes have been mainly considered as functionless evolutionary relics since their discovery in 1977. However, multiple mechanisms of pseudogene functionality have been proposed both at the transcriptional and post-transcriptional level. This review focuses on the role of pseudogenes as post-tr...

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Bibliographic Details
Published in:	Biochimie Vol. 93; no. 11; pp. 1916 - 1921
Main Authors:	Muro, Enrique M., Mah, Nancy, Andrade-Navarro, Miguel A.
Format:	Journal Article
Language:	English
Published:	France Elsevier B.V 01-11-2011
Subjects:	Animals Disease - genetics Evolution Evolution, Molecular Gene Expression Regulation Genomics Humans Mice MicroRNAs - genetics MicroRNAs - metabolism miRNA Natural antisense transcripts ncRNA Pseudogenes Pseudogenes - genetics RNA Processing, Post-Transcriptional - genetics RNA Stability - genetics RNA, Small Interfering - genetics RNA, Small Interfering - metabolism siRNA Transcription, Genetic miRNA siRNA Pseudogenes ncRNA Natural antisense transcripts
Online Access:	Get full text
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