Characteristics and Outcome of Children with Renal Cell Carcinoma: A Narrative Review

Pediatric renal cell carcinoma (RCC) is a rare type of kidney cancer, most commonly occurring in teenagers and young adolescents. Few relatively large series of pediatric RCC have been reported. Knowledge of clinical characteristics, outcome and treatment strategies are often based on the more frequ...

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Bibliographic Details
Published in:Cancers Vol. 12; no. 7; p. 1776
Main Authors: van der Beek, Justine N, Geller, James I, de Krijger, Ronald R, Graf, Norbert, Pritchard-Jones, Kathy, Drost, Jarno, Verschuur, Arnauld C, Murphy, Dermot, Ray, Satyajit, Spreafico, Filippo, Dzhuma, Kristina, Littooij, Annemieke S, Selle, Barbara, Tytgat, Godelieve A M, van den Heuvel-Eibrink, Marry M
Format: Journal Article
Language:English
Published: Switzerland MDPI 03-07-2020
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Summary:Pediatric renal cell carcinoma (RCC) is a rare type of kidney cancer, most commonly occurring in teenagers and young adolescents. Few relatively large series of pediatric RCC have been reported. Knowledge of clinical characteristics, outcome and treatment strategies are often based on the more frequently occurring adult types of RCC. However, published pediatric data suggest that clinical, molecular and histological characteristics of pediatric RCC differ from adult RCC. This paper summarizes reported series consisting of ≥10 RCC pediatric patients in order to create an up-to-date overview of the clinical and histopathological characteristics, treatment and outcome of pediatric RCC patients.
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ISSN:2072-6694
2072-6694
DOI:10.3390/cancers12071776