Pyomyositis as a focus of infection in hematological disorders: A report of 3 cases

The cases of 3 patients with pyomyositis associated with hematological disorders are reported. A 40-year-old man in the blastic phase of chronic myelogenous leukemia and 2 men aged 46 and 71 years with neutropenia due to myelodysplastic syndromes all reported high fever and severe local myalgia and...

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Published in:International journal of hematology Vol. 77; no. 2; pp. 171 - 174
Main Authors: HAYASHI, Tatsuyuki, NOZAKI, Miho, NONAKA, Yasunobu, OHASHI, Kazuteru, SAKAMAKI, Hisashi, NOMURA, Takeo
Format: Journal Article
Language:English
Published: Tokyo Springer 01-02-2003
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Abstract The cases of 3 patients with pyomyositis associated with hematological disorders are reported. A 40-year-old man in the blastic phase of chronic myelogenous leukemia and 2 men aged 46 and 71 years with neutropenia due to myelodysplastic syndromes all reported high fever and severe local myalgia and had marked elevation of C-reactive protein. Magnetic resonance imaging revealed muscle abscesses or fasciitis, and the findings led to the diagnosis of pyomyositis. Methicillin-resistant Staphylococcus aureus was isolated from the abscesses of 2 patients, and surgical drainage proved more effective than did antimicrobial agents. It should be recognized that pyomyositis is a possible source of infection in patients with hematological disorders.
AbstractList The cases of 3 patients with pyomyositis associated with hematological disorders are reported. A 40-year-old man in the blastic phase of chronic myelogenous leukemia and 2 men aged 46 and 71 years with neutropenia due to myelodysplastic syndromes all reported high fever and severe local myalgia and had marked elevation of C-reactive protein. Magnetic resonance imaging revealed muscle abscesses or fasciitis, and the findings led to the diagnosis of pyomyositis. Methicillin-resistant Staphylococcus aureus was isolated from the abscesses of 2 patients, and surgical drainage proved more effective than did antimicrobial agents. It should be recognized that pyomyositis is a possible source of infection in patients with hematological disorders.
The cases of 3 patients with pyomyositis associated with hematological disorders are reported. A 40-year-old man in the blastic phase of chronic myelogenous leukemia and 2 men aged 46 and 71 years with neutropenia due to myelodysplastic syndromes all reported high fever and severe local myalgia and had marked elevation of C-reactive protein. Magnetic resonance imaging revealed muscle abscesses or fasciitis, and the findings led to the diagnosis of pyomyositis. Methicillin-resistantStaphylococcus aureus was isolated from the abscesses of 2 patients, and surgical drainage proved more effective than did antimicrobial agents. It should be recognized that pyomyositis is a possible source of infection in patients with hematological disorders.
Author HAYASHI, Tatsuyuki
NOMURA, Takeo
SAKAMAKI, Hisashi
NOZAKI, Miho
NONAKA, Yasunobu
OHASHI, Kazuteru
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  surname: NOZAKI
  fullname: NOZAKI, Miho
  organization: Division of Internal Medicine, Tokyo Metropolitan Police Hospital, Tokyo, Japan
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  givenname: Yasunobu
  surname: NONAKA
  fullname: NONAKA, Yasunobu
  organization: Division of Internal Medicine, Tokyo Metropolitan Police Hospital, Tokyo, Japan
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  surname: NOMURA
  fullname: NOMURA, Takeo
  organization: Division of Internal Medicine, Tokyo Metropolitan Police Hospital, Tokyo, Japan
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Cites_doi 10.1016/S0140-6736(83)91281-3
10.1016/0035-9203(89)90678-0
10.1093/clind/15.4.668
10.1016/0049-0172(94)90090-6
10.1148/radiology.197.1.7568838
10.1016/0002-9610(79)90158-2
10.1136/bmj.299.6695.375
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IsPeerReviewed true
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Issue 2
Keywords Human
Opportunistic infection
Male
Malignant hemopathy
Nuclear magnetic resonance imaging
Infection
Case study
Striated muscle disease
Magnetic resonance imaging
Methicillin-resistant Staphylococcus aureus
Pyomyositis
Bacteriosis
Bacteria
Medical imagery
Micrococcales
Complication
Myositis
Micrococcaceae
Diagnosis
Hematological disorders
Staphylococcus aureus
Language English
License CC BY 4.0
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PublicationTitle International journal of hematology
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Springer Nature B.V
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Snippet The cases of 3 patients with pyomyositis associated with hematological disorders are reported. A 40-year-old man in the blastic phase of chronic myelogenous...
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StartPage 171
SubjectTerms Adult
Aged
Biological and medical sciences
Drug Resistance, Bacterial
Fatal Outcome
Hematologic and hematopoietic diseases
Hematologic Diseases - complications
Hematologic Diseases - drug therapy
Humans
Leukemias. Malignant lymphomas. Malignant reticulosis. Myelofibrosis
Magnetic Resonance Imaging
Male
Medical sciences
Methicillin
Middle Aged
Myositis - diagnosis
Myositis - drug therapy
Myositis - etiology
Neutropenia
Opportunistic Infections - diagnosis
Opportunistic Infections - drug therapy
Staphylococcal Infections - diagnosis
Staphylococcal Infections - drug therapy
Staphylococcal Infections - etiology
Staphylococcus aureus
Title Pyomyositis as a focus of infection in hematological disorders: A report of 3 cases
URI https://www.ncbi.nlm.nih.gov/pubmed/12627853
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