Pyomyositis as a focus of infection in hematological disorders: A report of 3 cases
The cases of 3 patients with pyomyositis associated with hematological disorders are reported. A 40-year-old man in the blastic phase of chronic myelogenous leukemia and 2 men aged 46 and 71 years with neutropenia due to myelodysplastic syndromes all reported high fever and severe local myalgia and...
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Published in: | International journal of hematology Vol. 77; no. 2; pp. 171 - 174 |
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Springer
01-02-2003
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Abstract | The cases of 3 patients with pyomyositis associated with hematological disorders are reported. A 40-year-old man in the blastic phase of chronic myelogenous leukemia and 2 men aged 46 and 71 years with neutropenia due to myelodysplastic syndromes all reported high fever and severe local myalgia and had marked elevation of C-reactive protein. Magnetic resonance imaging revealed muscle abscesses or fasciitis, and the findings led to the diagnosis of pyomyositis. Methicillin-resistant Staphylococcus aureus was isolated from the abscesses of 2 patients, and surgical drainage proved more effective than did antimicrobial agents. It should be recognized that pyomyositis is a possible source of infection in patients with hematological disorders. |
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AbstractList | The cases of 3 patients with pyomyositis associated with hematological disorders are reported. A 40-year-old man in the blastic phase of chronic myelogenous leukemia and 2 men aged 46 and 71 years with neutropenia due to myelodysplastic syndromes all reported high fever and severe local myalgia and had marked elevation of C-reactive protein. Magnetic resonance imaging revealed muscle abscesses or fasciitis, and the findings led to the diagnosis of pyomyositis. Methicillin-resistant Staphylococcus aureus was isolated from the abscesses of 2 patients, and surgical drainage proved more effective than did antimicrobial agents. It should be recognized that pyomyositis is a possible source of infection in patients with hematological disorders. The cases of 3 patients with pyomyositis associated with hematological disorders are reported. A 40-year-old man in the blastic phase of chronic myelogenous leukemia and 2 men aged 46 and 71 years with neutropenia due to myelodysplastic syndromes all reported high fever and severe local myalgia and had marked elevation of C-reactive protein. Magnetic resonance imaging revealed muscle abscesses or fasciitis, and the findings led to the diagnosis of pyomyositis. Methicillin-resistantStaphylococcus aureus was isolated from the abscesses of 2 patients, and surgical drainage proved more effective than did antimicrobial agents. It should be recognized that pyomyositis is a possible source of infection in patients with hematological disorders. |
Author | HAYASHI, Tatsuyuki NOMURA, Takeo SAKAMAKI, Hisashi NOZAKI, Miho NONAKA, Yasunobu OHASHI, Kazuteru |
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Cites_doi | 10.1016/S0140-6736(83)91281-3 10.1016/0035-9203(89)90678-0 10.1093/clind/15.4.668 10.1016/0049-0172(94)90090-6 10.1148/radiology.197.1.7568838 10.1016/0002-9610(79)90158-2 10.1136/bmj.299.6695.375 |
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Keywords | Human Opportunistic infection Male Malignant hemopathy Nuclear magnetic resonance imaging Infection Case study Striated muscle disease Magnetic resonance imaging Methicillin-resistant Staphylococcus aureus Pyomyositis Bacteriosis Bacteria Medical imagery Micrococcales Complication Myositis Micrococcaceae Diagnosis Hematological disorders Staphylococcus aureus |
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SubjectTerms | Adult Aged Biological and medical sciences Drug Resistance, Bacterial Fatal Outcome Hematologic and hematopoietic diseases Hematologic Diseases - complications Hematologic Diseases - drug therapy Humans Leukemias. Malignant lymphomas. Malignant reticulosis. Myelofibrosis Magnetic Resonance Imaging Male Medical sciences Methicillin Middle Aged Myositis - diagnosis Myositis - drug therapy Myositis - etiology Neutropenia Opportunistic Infections - diagnosis Opportunistic Infections - drug therapy Staphylococcal Infections - diagnosis Staphylococcal Infections - drug therapy Staphylococcal Infections - etiology Staphylococcus aureus |
Title | Pyomyositis as a focus of infection in hematological disorders: A report of 3 cases |
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