Verification of the BALB/c 3T3 cell transformation assay after improvement by using an ITES-medium

We carried out the first-step verification study on our ITES-medium-improved BALB/c 3T3 cell transformation assay. In order to estimate its potential use as a short-term screening method for putative carcinogens, 31 chemicals were tested in the improved transformation assay. The test chemicals consi...

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Bibliographic Details
Published in:	Toxicology in vitro Vol. 17; no. 4; pp. 489 - 496
Main Authors:	Kajiwara, Yoshitsugu, Ajimi, Syozo
Format:	Journal Article
Language:	English
Published:	England Elsevier Ltd 01-08-2003
Subjects:	3T3 Cells Animals BALB/c 3T3 cells Carcinogenicity Tests - methods Carcinogens - toxicity Cell Transformation, Neoplastic - drug effects Culture Media - chemistry Dose-Response Relationship, Drug Improved cell transformation assay ITES-medium Mice Mice, Inbred BALB C Nongenotoxic carcinogens Reproducibility of Results BALB/c 3T3 cells Nongenotoxic carcinogens ITES-medium Improved cell transformation assay EPA
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