Glucocorticosteroids up-regulate the expression of cholecystokinin mRNA in the rat paraventricular nucleus

Adrenalectomy abolishes corticosteroid feedback onto the hypothalamic–pituitary–adrenal axis. This results in an increased biosynthetic and secretory activity of corticotropin-releasing hormone (CRH) neurons of the hypothalamic paraventricular nucleus (PVN), sustained in the absence of hormone repla...

Full description

Saved in:

Bibliographic Details
Published in:	Brain research Vol. 877; no. 2; pp. 412 - 423
Main Authors:	Cournil, Isabelle, Lafon, Pierrette, Juaneda, Christian, Ciofi, Philippe, Fournier, Marie-Christine, Sarrieau, Alain, Tramu, Gérard
Format:	Journal Article
Language:	English
Published:	Netherlands Elsevier B.V 22-09-2000
Subjects:	Adrenalectomy - adverse effects Animals Cholecystokinin - genetics Cholecystokinin - metabolism Circadian Rhythm - drug effects Circadian Rhythm - physiology Corticosterone feedback Corticotropin-Releasing Hormone - drug effects Corticotropin-Releasing Hormone - genetics Corticotropin-Releasing Hormone - metabolism CRH mRNA Feedback - drug effects Feedback - physiology Glucocorticoids - metabolism Glucocorticoids - pharmacology Hypothalamic–pituitary–adrenal axis Hypothalamo-Hypophyseal System - cytology Hypothalamo-Hypophyseal System - drug effects Hypothalamo-Hypophyseal System - metabolism Male Neurons - drug effects Neurons - metabolism Neuropeptide Oxytocin - drug effects Oxytocin - genetics Oxytocin - metabolism Paraventricular Hypothalamic Nucleus - cytology Paraventricular Hypothalamic Nucleus - drug effects Paraventricular Hypothalamic Nucleus - metabolism Quantitative in situ hybridization Rats Rats, Wistar RNA, Messenger - drug effects RNA, Messenger - metabolism Up-Regulation - drug effects Up-Regulation - physiology Endocrine and autonomic regulation Hypothalamic–pituitary–adrenal axis Quantitative in situ hybridization Neuropeptide Corticosterone feedback CRH mRNA
Online Access:	Get full text
Tags:	Add Tag No Tags, Be the first to tag this record!

Be the first to leave a comment!