A rare cause of nephrotic syndrome in autosomal-dominant polycystic kidney disease

We report the case of a 49-year-old lady who presented with hypertension, breathlessness and malaise. She was thrombocytopenic, with polycystic kidneys on imaging, and was found to have nephrotic syndrome. Serological results were consistent with systemic lupus erythematosus (SLE) and a renal biopsy...

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Bibliographic Details
Published in:	NDT plus Vol. 2; no. 2; pp. 136 - 138
Main Authors:	Wan, Ray K, Kipgen, David, Morris, Scott, Rodger, R Stuart C
Format:	Journal Article
Language:	English
Published:	England Oxford University Press 01-04-2009
Subjects:	Case Report polycystic lupus nephrotic syndrome
Online Access:	Get full text
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Summary:	We report the case of a 49-year-old lady who presented with hypertension, breathlessness and malaise. She was thrombocytopenic, with polycystic kidneys on imaging, and was found to have nephrotic syndrome. Serological results were consistent with systemic lupus erythematosus (SLE) and a renal biopsy confirmed WHO class V lupus nephritis. This is the first reported case of nephrotic syndrome due to lupus nephritis in a patient with autosomal dominant polycystic kidney disease (ADPKD) and underlines the importance of renal biopsy in patients with ADPKD and nephrotic range proteinuria.
ISSN:	1753-0784 1753-0792
DOI:	10.1093/ndtplus/sfn197