Tumor debulking by radiofrequency ablation in hypertrophic pulmonary osteoarthropathy associated with pulmonary carcinoma

A 73-year-old male with stage IV lung adenocarcinoma presented with leg swelling and clubbing of the fingers on both hands upon physical examination, and bone scintigrams demonstrated marked accumulation of 99mTc-MDP in the long bones adjacent to the patellae. A diagnosis of hypertrophic pulmonary o...

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Bibliographic Details
Published in:	Lung cancer (Amsterdam, Netherlands) Vol. 38; no. 3; pp. 317 - 320
Main Authors:	Kishi, Koji, Nakamura, Hiroyuki, Sudo, Akihiko, Kobayashi, Katsuyuki, Yagyu, Hisanaga, Oh-ishi, Shuji, Matsuoka, Takeshi
Format:	Journal Article
Language:	English
Published:	Shannon Elsevier Ireland Ltd 01-12-2002 Elsevier Science
Subjects:	Adenocarcinoma - complications Adenocarcinoma - surgery Aged Biological and medical sciences Catheter Ablation Humans Hypertrophic pulmonary osteoarthropathy Lung cancer Lung Neoplasms - complications Lung Neoplasms - surgery Male Medical sciences Osteoarthropathy, Secondary Hypertrophic - diagnosis Osteoarthropathy, Secondary Hypertrophic - etiology Pneumology Radiofrequency ablation Tumor Tumors of the respiratory system and mediastinum Hypertrophic pulmonary osteoarthropathy Radiofrequency ablation Tumor Lung cancer Human Lung disease Carcinoma Respiratory disease Hypertrophic pulmonary arthropathy Lung Cytoreduction Malignant tumor Radiofrequency Ablation Bronchopulmonary Association Treatment Bronchus disease Elderly
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Summary:	A 73-year-old male with stage IV lung adenocarcinoma presented with leg swelling and clubbing of the fingers on both hands upon physical examination, and bone scintigrams demonstrated marked accumulation of 99mTc-MDP in the long bones adjacent to the patellae. A diagnosis of hypertrophic pulmonary osteoarthropathy associated with primary lung cancer was made. Radiofrequency ablation (RFA) was utilized for cytoreduction, because the patient refused chemotherapy. One-month follow-up CT scans revealed low density of the ablated area associated with ablation necrosis. Cytoreduction by RFA rapidly alleviated the arthralgia and swelling, but not the clubbing of fingers. Follow-up bone scintigrams demonstrated a reduction in patellar uptake after RFA.
Bibliography:	ObjectType-Case Study-2 SourceType-Scholarly Journals-1 ObjectType-Feature-4 content type line 23 ObjectType-Report-1 ObjectType-Article-3
ISSN:	0169-5002 1872-8332
DOI:	10.1016/S0169-5002(02)00217-9