TAMOXIFEN INHIBITION OF AN in vitro OESTRADIOL‐INDUCED SURFACE COAT CHANGE ON MOUSE BLASTOCYSTS

1 Eighty‐nine hour post‐coitus mouse blastocysts cultured in the presence of oestradiol‐17β underwent a histochemically detectable surface coat change. 2 Tamoxifen was found to inhibit this in vitro ‐induced change. The role of Tamoxifen as an inhibitor of implantation is discussed.

Saved in:

Bibliographic Details
Published in:	British journal of pharmacology Vol. 60; no. 4; pp. 517 - 519
Main Authors:	BLOXHAM, P.A., PUGH, D.M.
Format:	Journal Article
Language:	English
Published:	Oxford, UK Blackwell Publishing Ltd 01-08-1977
Subjects:	Animals Blastocyst - drug effects Blastocyst - ultrastructure Estradiol - pharmacology Estrogen Antagonists In Vitro Techniques Mice Tamoxifen - pharmacology Time Factors
Online Access:	Get full text
Tags:	Add Tag No Tags, Be the first to tag this record!

Description
Summary:	1 Eighty‐nine hour post‐coitus mouse blastocysts cultured in the presence of oestradiol‐17β underwent a histochemically detectable surface coat change. 2 Tamoxifen was found to inhibit this in vitro ‐induced change. The role of Tamoxifen as an inhibitor of implantation is discussed.
Bibliography:	ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23
ISSN:	0007-1188 1476-5381
DOI:	10.1111/j.1476-5381.1977.tb07529.x