miR-374a-5p promotes tumor progression by targeting ARRB1 in triple negative breast cancer

Triple negative breast cancer (TNBC) has higher aggressiveness and poorer outcomes compared with other subtypes of breast cancer. However, the genomic and molecular aberrations of TNBC are largely unknown. In this study, miR-374a-5p was discovered as a novel TNBC-specific miRNA and its functions and...

Full description

Saved in:

Bibliographic Details
Published in:	Cancer letters Vol. 454; pp. 224 - 233
Main Authors:	Son, Dasom, Kim, Yesol, Lim, Sera, Kang, Hyeok-Gu, Kim, Da-Hyun, Park, Jee Won, Cheong, Woosung, Kong, Hyun Kyung, Han, Wonshik, Park, Woong-Yang, Chun, Kyung-Hee, Park, Jong Hoon
Format:	Journal Article
Language:	English
Published:	Ireland Elsevier B.V 10-07-2019 Elsevier Limited
Subjects:	AMP-Activated Protein Kinases - genetics AMP-Activated Protein Kinases - metabolism AMPKα Arrestin Arrestin beta 1 beta-Arrestin 1 - biosynthesis beta-Arrestin 1 - genetics beta-Arrestin 1 - metabolism Breast cancer Cell growth Cell Line, Tumor Cell migration Cell Movement - physiology Cell Proliferation - physiology Cell Survival - physiology Disease Progression DNA microarrays Enzyme Activation Female Gene expression Genes HEK293 Cells Humans Kinases MCF-7 Cells Medical prognosis Metastasis MicroRNAs - genetics MicroRNAs - metabolism Migration miR-374a-5p miRNA Molecular modelling Proteins Studies Triple negative breast cancer Triple Negative Breast Neoplasms - genetics Triple Negative Breast Neoplasms - metabolism Triple Negative Breast Neoplasms - pathology Up-Regulation United States > US South Korea Arrestin beta 1 Lum A miR-374a-5p AMPKα Lum B 3′UTR miRNA ARRB1 TNBC HER2 Triple negative breast cancer
Online Access:	Get full text
Tags:	Add Tag No Tags, Be the first to tag this record!

Be the first to leave a comment!