Saponin with antibacterial activity from the roots of Albizia adianthifolia

An unprecedented saponin is being reported herein together with five known compounds from the methanol extract of the roots of Albizia adianthifolia. The metabolites were obtained over repeated open column chromatography methods and spectroscopic followed by spectrometric techniques. The isolated co...

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Bibliographic Details
Published in:	Natural product research Vol. 35; no. 17; pp. 2831 - 2839
Main Authors:	Sonfack, Gaiëlle, Fossi Tchinda, Cedric, Simo, Ingrid Konga, Bitchagno, Gabin Thierry M., Nganou, Blaise Kemajou, Çelik, İlhami, Tene, Mathieu, Funda Görkem, Sultan, Opatz, Till, Penlap Beng, Veronique, Kuete, Victor, Tane, Pierre
Format:	Journal Article
Language:	English
Published:	Taylor & Francis 19-08-2021
Subjects:	adianthifolioside Albizia adianthifolia; Mimosaceae antibacterial saponin
Online Access:	Get full text
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Summary:	An unprecedented saponin is being reported herein together with five known compounds from the methanol extract of the roots of Albizia adianthifolia. The metabolites were obtained over repeated open column chromatography methods and spectroscopic followed by spectrometric techniques. The isolated compounds were tested against eleven Gram-negative bacteria including multidrug resistant strains. The results revealed considerable inhibition of the new saponin against the studied bacteria with MIC values ranging from 16 to 128 μg/mL.
Bibliography:	ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23
ISSN:	1478-6419 1478-6427
DOI:	10.1080/14786419.2019.1672689