Beneficial effects of 1-year captopril therapy in children with chronic aortic regurgitation who have no symptoms

Objective This prospective study was performed to assess the effects of 1 year of angiotensin-converting enzyme inhibition with captopril in 20 children (mean age 14.3 ± 2.3 years) with asymptomatic chronic aortic regurgitation. Methods and Results At 12 months patients receiving captopril had a sig...

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Bibliographic Details
Published in:	The American heart journal Vol. 135; no. 4; pp. 598 - 603
Main Authors:	Alehan, Dursun, Özkutlu, Süheyla
Format:	Journal Article
Language:	English
Published:	New York, NY Mosby, Inc 01-04-1998 Elsevier
Subjects:	Administration, Oral Adolescent Angiotensin-Converting Enzyme Inhibitors - administration & dosage Angiotensin-Converting Enzyme Inhibitors - therapeutic use Aortic Valve Insufficiency - diagnosis Aortic Valve Insufficiency - drug therapy Aortic Valve Insufficiency - physiopathology Biological and medical sciences Captopril - administration & dosage Captopril - therapeutic use Cardiovascular system Child Chronic Disease Dose-Response Relationship, Drug Echocardiography Electrocardiography Female Follow-Up Studies Heart Rate - drug effects Humans Male Medical sciences Miscellaneous Myocardial Contraction - drug effects Pharmacology. Drug treatments Prospective Studies Radiography, Thoracic Stroke Volume - drug effects Treatment Outcome Tropical medicine Sonography Human Echocardiography Captopril Cardiovascular disease Asymptomatic Aortic regurgitation Long term Left ventricle Chemotherapy Treatment Cardiac valvular disease Mechanism of action Child Aortic valve ACE inhibitor
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