Localization of intestinal pacemaker cells and synapses in the muscle layers of a patient with colonic hypoganglionosis

Bowel dysmotility in association with hypoganglionosis remains unexplained. The proto-oncogene c- kit encodes a transmembrane tyrosine kinase receptor, and the c- kit protein-product (C-KIT) positive cells in the mammalian gut are responsible for intestinal pacemaker activity. The authors examined t...

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Bibliographic Details
Published in:Journal of pediatric surgery Vol. 31; no. 4; pp. 584 - 587
Main Authors: Yamataka, A., Fujiwara, T., Nishiye, H., Sunagawa, M., Miyano, T.
Format: Journal Article Conference Proceeding
Language:English
Published: Philadelphia, PA Elsevier Inc 01-04-1996
Elsevier
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