Primary malignant melanoma of the common bile duct

Biliary tract obstruction in a 30-year-old man was found to be caused by a malignant melanoma in the common bile duct. Melanin pigment was demonstrated by immunohistochemistry and electron microscopy. Extensive search for a primary malignant melanoma elsewhere was unsuccessful. No pigmented lesions...

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Published in:	Human pathology Vol. 17; no. 12; p. 1282
Main Authors:	Carstens, H B, Ghazi, C, Carnighan, R H, Brewer, M S
Format:	Journal Article
Language:	English
Published:	United States 01-12-1986
Subjects:	Adult Biopsy Common Bile Duct Neoplasms - pathology Common Bile Duct Neoplasms - surgery Humans Liver - pathology Male Melanoma - pathology Melanoma - surgery
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Abstract	Biliary tract obstruction in a 30-year-old man was found to be caused by a malignant melanoma in the common bile duct. Melanin pigment was demonstrated by immunohistochemistry and electron microscopy. Extensive search for a primary malignant melanoma elsewhere was unsuccessful. No pigmented lesions had been removed previously. There were junctional changes in the mucosa of the common bile duct close to the tumor. The malignant melanoma in the common bile duct therefore is considered to be primary. Only one other case of primary malignant melanoma in the common bile duct has been described in the literature, whereas metastases to the major bile ducts in one autopsy study of malignant melanoma in the more common locations were found with a frequency of 6 per cent.
AbstractList	Biliary tract obstruction in a 30-year-old man was found to be caused by a malignant melanoma in the common bile duct. Melanin pigment was demonstrated by immunohistochemistry and electron microscopy. Extensive search for a primary malignant melanoma elsewhere was unsuccessful. No pigmented lesions had been removed previously. There were junctional changes in the mucosa of the common bile duct close to the tumor. The malignant melanoma in the common bile duct therefore is considered to be primary. Only one other case of primary malignant melanoma in the common bile duct has been described in the literature, whereas metastases to the major bile ducts in one autopsy study of malignant melanoma in the more common locations were found with a frequency of 6 per cent.
Author	Carnighan, R H Ghazi, C Brewer, M S Carstens, H B
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BackLink	https://www.ncbi.nlm.nih.gov/pubmed/3793088$$D View this record in MEDLINE/PubMed
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CitedBy_id	crossref_primary_10_1016_j_ijscr_2012_05_008 crossref_primary_10_1007_BF03044826 crossref_primary_10_1016_S0399_8320_05_82186_4 crossref_primary_10_1016_j_pathol_2022_07_012 crossref_primary_10_5858_2000_124_0419_PMMOTC crossref_primary_10_1080_01913120701465510 crossref_primary_10_14309_crj_2016_101 crossref_primary_10_1177_03000605231164005 crossref_primary_10_1053_j_semdp_2003_08_007 crossref_primary_10_12998_wjcc_v7_i16_2302 crossref_primary_10_1002_lt_500010206 crossref_primary_10_1157_13077759 crossref_primary_10_1007_s002619900103
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Title	Primary malignant melanoma of the common bile duct
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