Recommendations for hypofractionated whole-breast irradiation

This recommendation consensus for hypofractionated whole-breast radiotherapy (RT) was organized by the Brazilian Society of Radiotherapy (SBRT) considering the optimal scenario for indication and safety in the technology applied. All controversies and contraindication matters (hypofractionated RT in...

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Published in:Revista da Associacao Medica Brasileira (1992) Vol. 64; no. 9; pp. 770 - 777
Main Authors: Freitas, Nilceana Maya Aires, Rosa, Arthur Accioly, Marta, Gustavo Nader, Hanna, Samir Abdalla, Hanriot, Rodrigo de Morais, Borges, Allisson Bruno Barcelos, Gondim, Guilherme Rocha Melo, Pellizzon, Antonio Cassio Assis, Veras, Igor Moreira, Almeida Júnior, Wilson José de, Fernandez, Claudia Regina Scaramello Hadlich Willis, Batalha Filho, Eronides Salustiano, Castilho, Marcus Simões, Kuhnen, Felipe Quintino, Najas, Rosa Maria Xavier Faria, Affonso Júnior, Renato José, Leite, André Campana Correia, Ribeiro, Homero Lavieri Martins, Freitas Junior, Ruffo, Oliveira, Harley Francisco de
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Abstract This recommendation consensus for hypofractionated whole-breast radiotherapy (RT) was organized by the Brazilian Society of Radiotherapy (SBRT) considering the optimal scenario for indication and safety in the technology applied. All controversies and contraindication matters (hypofractionated RT in patients who underwent chemotherapy [CT], hypofractionated RT in lymphatic drainage, hypofractionated RT after mastectomy with or without immediate reconstruction, boost during surgery, hypofractionated RT in patients under 50 years old, hypofractionated RT in large breasts, hypofractionated RT in histology of carcinoma in situ [DCIS]) was discussed during a meeting in person, and a consensus was reached when there was an agreement of at least 75% among panel members. The grade for recommendation was also suggested according to the level of scientific evidence available, qualified as weak, medium, or strong. Thus, this consensus will aid Brazilian radiotherapy experts regarding indications and particularities of this technique as a viable and safe alternative for the national reality.
AbstractList SUMMARY This recommendation consensus for hypofractionated whole-breast radiotherapy (RT) was organized by the Brazilian Society of Radiotherapy (SBRT) considering the optimal scenario for indication and safety in the technology applied. All controversies and contraindication matters (hypofractionated RT in patients who underwent chemotherapy [CT], hypofractionated RT in lymphatic drainage, hypofractionated RT after mastectomy with or without immediate reconstruction, boost during surgery, hypofractionated RT in patients under 50 years old, hypofractionated RT in large breasts, hypofractionated RT in histology of carcinoma in situ [DCIS]) was discussed during a meeting in person, and a consensus was reached when there was an agreement of at least 75% among panel members. The grade for recommendation was also suggested according to the level of scientific evidence available, qualified as weak, medium, or strong. Thus, this consensus will aid Brazilian radiotherapy experts regarding indications and particularities of this technique as a viable and safe alternative for the national reality. RESUMO Este consenso de recomendações para a radioterapia (RT) hipofracionada de toda a mama foi organizado pela Sociedade Brasileira de Radioterapia (SBRT) considerando o cenário ideal para indicação e segurança na tecnologia aplicada. Questões de controvérsias e contraindicações (RT hipofracionada em pacientes submetidas à quimioterapia [QT], RT hipofracionada nas drenagens linfáticas, RT hipofracionada após mastectomia com ou sem reconstrução imediata, a realização de reforço de dose em leito cirúrgico [ou boost], RT hipofracionada em pacientes com idade menor que 50 anos, RT hipofracionada em mamas volumosas, RT hipofracionada em histologia de carcinoma in situ [CDIS]) foram discutidas em encontro presencial, sendo o consenso atingido quando existisse concordância de pelo menos 75% dos panelistas. O grau de recomendação foi também sugerido de acordo com o nível de evidência científico disponível, qualificado entre fraco, médio ou forte. Assim, este consenso deverá servir para auxiliar os especialistas da radioterapia brasileira em relação às indicações e particularidades dessa técnica, como uma alternativa segura e viável para a realidade nacional.
This recommendation consensus for hypofractionated whole-breast radiotherapy (RT) was organized by the Brazilian Society of Radiotherapy (SBRT) considering the optimal scenario for indication and safety in the technology applied. All controversies and contraindication matters (hypofractionated RT in patients who underwent chemotherapy [CT], hypofractionated RT in lymphatic drainage, hypofractionated RT after mastectomy with or without immediate reconstruction, boost during surgery, hypofractionated RT in patients under 50 years old, hypofractionated RT in large breasts, hypofractionated RT in histology of carcinoma in situ [DCIS]) was discussed during a meeting in person, and a consensus was reached when there was an agreement of at least 75% among panel members. The grade for recommendation was also suggested according to the level of scientific evidence available, qualified as weak, medium, or strong. Thus, this consensus will aid Brazilian radiotherapy experts regarding indications and particularities of this technique as a viable and safe alternative for the national reality.
Author Marta, Gustavo Nader
Pellizzon, Antonio Cassio Assis
Najas, Rosa Maria Xavier Faria
Veras, Igor Moreira
Oliveira, Harley Francisco de
Ribeiro, Homero Lavieri Martins
Borges, Allisson Bruno Barcelos
Kuhnen, Felipe Quintino
Leite, André Campana Correia
Freitas Junior, Ruffo
Almeida Júnior, Wilson José de
Hanriot, Rodrigo de Morais
Rosa, Arthur Accioly
Hanna, Samir Abdalla
Gondim, Guilherme Rocha Melo
Castilho, Marcus Simões
Freitas, Nilceana Maya Aires
Batalha Filho, Eronides Salustiano
Affonso Júnior, Renato José
Fernandez, Claudia Regina Scaramello Hadlich Willis
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  givenname: Nilceana Maya Aires
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  surname: Freitas
  fullname: Freitas, Nilceana Maya Aires
  organization: . Radiotherapy Department of the Araújo Jorge Hospital of the Góias State Association Against Cancer, Goiânia/GO, Brasil
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  givenname: Arthur Accioly
  surname: Rosa
  fullname: Rosa, Arthur Accioly
  organization: . Radiotherapy Department of the Bahia State Portuguese Hospital, Salvador/BA and President of the Brazilian Radiotherapy Society (SBRT), São Paulo/SP, Brasil
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  givenname: Gustavo Nader
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  surname: Marta
  fullname: Marta, Gustavo Nader
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  givenname: Samir Abdalla
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  givenname: Allisson Bruno Barcelos
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  givenname: Guilherme Rocha Melo
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  givenname: Antonio Cassio Assis
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  organization: . Radiotherapy Department of the AC Camargo Hospital, São Paulo/SP, Brasil
– sequence: 9
  givenname: Igor Moreira
  surname: Veras
  fullname: Veras, Igor Moreira
  organization: . Radiotherapy Department of the Regional Integrated Oncology Center, Fortaleza-CE
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  givenname: Wilson José de
  surname: Almeida Júnior
  fullname: Almeida Júnior, Wilson José de
  organization: . Radiotherapy Department of the Moinhos dos Ventos Hospital, Porto Alegre-RS
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  givenname: Claudia Regina Scaramello Hadlich Willis
  surname: Fernandez
  fullname: Fernandez, Claudia Regina Scaramello Hadlich Willis
  organization: . Radiotherapy Service of the José Alencar Gomes da Silva National Cancer Institute, Rio de Janeiro/RJ, Brasil
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  givenname: Eronides Salustiano
  surname: Batalha Filho
  fullname: Batalha Filho, Eronides Salustiano
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  givenname: Marcus Simões
  surname: Castilho
  fullname: Castilho, Marcus Simões
– sequence: 14
  givenname: Felipe Quintino
  surname: Kuhnen
  fullname: Kuhnen, Felipe Quintino
  organization: . Radiotherapy Department of the Felicio Rocho Hospital, Belo Horizonte/MG, Brasil
– sequence: 15
  givenname: Rosa Maria Xavier Faria
  surname: Najas
  fullname: Najas, Rosa Maria Xavier Faria
  organization: . Radiotherapy Department of the Charity Hospital of Florianópolis, Florianópolis/SC, Brasil
– sequence: 16
  givenname: Renato José
  surname: Affonso Júnior
  fullname: Affonso Júnior, Renato José
  organization: . Radiotherapy Department, Barretos Cancer Hospital, Barretos/SP, Brasil
– sequence: 17
  givenname: André Campana Correia
  surname: Leite
  fullname: Leite, André Campana Correia
  organization: . Radiotherapy Department of the Rio Grande do Norte State League Against Cancer, Natal/RN, Brasil
– sequence: 18
  givenname: Homero Lavieri Martins
  surname: Ribeiro
  fullname: Ribeiro, Homero Lavieri Martins
  organization: . Department of Radiation Oncology, Fundação Centro de Controle de Oncologia Manaus- AM
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  givenname: Ruffo
  orcidid: 0000-0003-4145-8598
  surname: Freitas Junior
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  givenname: Harley Francisco de
  orcidid: 0000-0002-7408-5137
  surname: Oliveira
  fullname: Oliveira, Harley Francisco de
  organization: . Centro de Tratamento em Radio-Oncologia (CTR) and Ribeirão Preto Medical School (FMRP) da Universidade de São Paulo (USP) - Ribeirão Preto/SP; Hospital Márcio Cunha (HMC) - Ipatinga/MG, Brasil
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  article-title: Systematic review and meta-analysis comparing hypofractionated with conventional fraction radiotherapy in treatment of early breast cancer
  publication-title: Surg Oncol
  doi: 10.1016/j.suronc.2015.06.005
  contributor:
    fullname: Zhou Z-R
– year: 2011
  ident: ref9
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Snippet This recommendation consensus for hypofractionated whole-breast radiotherapy (RT) was organized by the Brazilian Society of Radiotherapy (SBRT) considering the...
SUMMARY This recommendation consensus for hypofractionated whole-breast radiotherapy (RT) was organized by the Brazilian Society of Radiotherapy (SBRT)...
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StartPage 770
SubjectTerms Brazil
Breast - radiation effects
Breast Neoplasms - pathology
Breast Neoplasms - radiotherapy
Carcinoma - pathology
Carcinoma - radiotherapy
Evidence-Based Medicine
Female
Humans
Radiation Dose Hypofractionation - standards
Risk Factors
Title Recommendations for hypofractionated whole-breast irradiation
URI https://www.ncbi.nlm.nih.gov/pubmed/30672995
Volume 64
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