Recommendations for hypofractionated whole-breast irradiation
This recommendation consensus for hypofractionated whole-breast radiotherapy (RT) was organized by the Brazilian Society of Radiotherapy (SBRT) considering the optimal scenario for indication and safety in the technology applied. All controversies and contraindication matters (hypofractionated RT in...
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Published in: | Revista da Associacao Medica Brasileira (1992) Vol. 64; no. 9; pp. 770 - 777 |
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01-09-2018
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Abstract | This recommendation consensus for hypofractionated whole-breast radiotherapy (RT) was organized by the Brazilian Society of Radiotherapy (SBRT) considering the optimal scenario for indication and safety in the technology applied. All controversies and contraindication matters (hypofractionated RT in patients who underwent chemotherapy [CT], hypofractionated RT in lymphatic drainage, hypofractionated RT after mastectomy with or without immediate reconstruction, boost during surgery, hypofractionated RT in patients under 50 years old, hypofractionated RT in large breasts, hypofractionated RT in histology of carcinoma in situ [DCIS]) was discussed during a meeting in person, and a consensus was reached when there was an agreement of at least 75% among panel members. The grade for recommendation was also suggested according to the level of scientific evidence available, qualified as weak, medium, or strong. Thus, this consensus will aid Brazilian radiotherapy experts regarding indications and particularities of this technique as a viable and safe alternative for the national reality. |
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AbstractList | SUMMARY This recommendation consensus for hypofractionated whole-breast radiotherapy (RT) was organized by the Brazilian Society of Radiotherapy (SBRT) considering the optimal scenario for indication and safety in the technology applied. All controversies and contraindication matters (hypofractionated RT in patients who underwent chemotherapy [CT], hypofractionated RT in lymphatic drainage, hypofractionated RT after mastectomy with or without immediate reconstruction, boost during surgery, hypofractionated RT in patients under 50 years old, hypofractionated RT in large breasts, hypofractionated RT in histology of carcinoma in situ [DCIS]) was discussed during a meeting in person, and a consensus was reached when there was an agreement of at least 75% among panel members. The grade for recommendation was also suggested according to the level of scientific evidence available, qualified as weak, medium, or strong. Thus, this consensus will aid Brazilian radiotherapy experts regarding indications and particularities of this technique as a viable and safe alternative for the national reality.
RESUMO Este consenso de recomendações para a radioterapia (RT) hipofracionada de toda a mama foi organizado pela Sociedade Brasileira de Radioterapia (SBRT) considerando o cenário ideal para indicação e segurança na tecnologia aplicada. Questões de controvérsias e contraindicações (RT hipofracionada em pacientes submetidas à quimioterapia [QT], RT hipofracionada nas drenagens linfáticas, RT hipofracionada após mastectomia com ou sem reconstrução imediata, a realização de reforço de dose em leito cirúrgico [ou boost], RT hipofracionada em pacientes com idade menor que 50 anos, RT hipofracionada em mamas volumosas, RT hipofracionada em histologia de carcinoma in situ [CDIS]) foram discutidas em encontro presencial, sendo o consenso atingido quando existisse concordância de pelo menos 75% dos panelistas. O grau de recomendação foi também sugerido de acordo com o nível de evidência científico disponível, qualificado entre fraco, médio ou forte. Assim, este consenso deverá servir para auxiliar os especialistas da radioterapia brasileira em relação às indicações e particularidades dessa técnica, como uma alternativa segura e viável para a realidade nacional. This recommendation consensus for hypofractionated whole-breast radiotherapy (RT) was organized by the Brazilian Society of Radiotherapy (SBRT) considering the optimal scenario for indication and safety in the technology applied. All controversies and contraindication matters (hypofractionated RT in patients who underwent chemotherapy [CT], hypofractionated RT in lymphatic drainage, hypofractionated RT after mastectomy with or without immediate reconstruction, boost during surgery, hypofractionated RT in patients under 50 years old, hypofractionated RT in large breasts, hypofractionated RT in histology of carcinoma in situ [DCIS]) was discussed during a meeting in person, and a consensus was reached when there was an agreement of at least 75% among panel members. The grade for recommendation was also suggested according to the level of scientific evidence available, qualified as weak, medium, or strong. Thus, this consensus will aid Brazilian radiotherapy experts regarding indications and particularities of this technique as a viable and safe alternative for the national reality. |
Author | Marta, Gustavo Nader Pellizzon, Antonio Cassio Assis Najas, Rosa Maria Xavier Faria Veras, Igor Moreira Oliveira, Harley Francisco de Ribeiro, Homero Lavieri Martins Borges, Allisson Bruno Barcelos Kuhnen, Felipe Quintino Leite, André Campana Correia Freitas Junior, Ruffo Almeida Júnior, Wilson José de Hanriot, Rodrigo de Morais Rosa, Arthur Accioly Hanna, Samir Abdalla Gondim, Guilherme Rocha Melo Castilho, Marcus Simões Freitas, Nilceana Maya Aires Batalha Filho, Eronides Salustiano Affonso Júnior, Renato José Fernandez, Claudia Regina Scaramello Hadlich Willis |
Author_xml | – sequence: 1 givenname: Nilceana Maya Aires orcidid: 0000-0002-9445-8674 surname: Freitas fullname: Freitas, Nilceana Maya Aires organization: . Radiotherapy Department of the Araújo Jorge Hospital of the Góias State Association Against Cancer, Goiânia/GO, Brasil – sequence: 2 givenname: Arthur Accioly surname: Rosa fullname: Rosa, Arthur Accioly organization: . Radiotherapy Department of the Bahia State Portuguese Hospital, Salvador/BA and President of the Brazilian Radiotherapy Society (SBRT), São Paulo/SP, Brasil – sequence: 3 givenname: Gustavo Nader orcidid: 0000-0002-3298-3684 surname: Marta fullname: Marta, Gustavo Nader organization: . Department of Radiation Oncology, Hospital Sírio-Libanês, São Paulo, Brazil – sequence: 4 givenname: Samir Abdalla surname: Hanna fullname: Hanna, Samir Abdalla organization: . Department of Radiation Oncology, Hospital Sírio-Libanês, São Paulo, Brazil – sequence: 5 givenname: Rodrigo de Morais surname: Hanriot fullname: Hanriot, Rodrigo de Morais organization: . Radiotherapy Department of the Oswaldo Cruz German Hospital, São Paulo/SP, Brasil – sequence: 6 givenname: Allisson Bruno Barcelos surname: Borges fullname: Borges, Allisson Bruno Barcelos organization: . Radiotherapy Department, Barretos Cancer Hospital, Barretos/SP, Brasil – sequence: 7 givenname: Guilherme Rocha Melo surname: Gondim fullname: Gondim, Guilherme Rocha Melo organization: . Radiotherapy Department of the AC Camargo Hospital, São Paulo/SP, Brasil – sequence: 8 givenname: Antonio Cassio Assis surname: Pellizzon fullname: Pellizzon, Antonio Cassio Assis organization: . Radiotherapy Department of the AC Camargo Hospital, São Paulo/SP, Brasil – sequence: 9 givenname: Igor Moreira surname: Veras fullname: Veras, Igor Moreira organization: . Radiotherapy Department of the Regional Integrated Oncology Center, Fortaleza-CE – sequence: 10 givenname: Wilson José de surname: Almeida Júnior fullname: Almeida Júnior, Wilson José de organization: . Radiotherapy Department of the Moinhos dos Ventos Hospital, Porto Alegre-RS – sequence: 11 givenname: Claudia Regina Scaramello Hadlich Willis surname: Fernandez fullname: Fernandez, Claudia Regina Scaramello Hadlich Willis organization: . Radiotherapy Service of the José Alencar Gomes da Silva National Cancer Institute, Rio de Janeiro/RJ, Brasil – sequence: 12 givenname: Eronides Salustiano surname: Batalha Filho fullname: Batalha Filho, Eronides Salustiano organization: . Radiotherapy Department of the Brasilia State University Hospital and representative of the Ministry of Health, Brasíli/DF, Brasil – sequence: 13 givenname: Marcus Simões surname: Castilho fullname: Castilho, Marcus Simões – sequence: 14 givenname: Felipe Quintino surname: Kuhnen fullname: Kuhnen, Felipe Quintino organization: . Radiotherapy Department of the Felicio Rocho Hospital, Belo Horizonte/MG, Brasil – sequence: 15 givenname: Rosa Maria Xavier Faria surname: Najas fullname: Najas, Rosa Maria Xavier Faria organization: . Radiotherapy Department of the Charity Hospital of Florianópolis, Florianópolis/SC, Brasil – sequence: 16 givenname: Renato José surname: Affonso Júnior fullname: Affonso Júnior, Renato José organization: . Radiotherapy Department, Barretos Cancer Hospital, Barretos/SP, Brasil – sequence: 17 givenname: André Campana Correia surname: Leite fullname: Leite, André Campana Correia organization: . Radiotherapy Department of the Rio Grande do Norte State League Against Cancer, Natal/RN, Brasil – sequence: 18 givenname: Homero Lavieri Martins surname: Ribeiro fullname: Ribeiro, Homero Lavieri Martins organization: . Department of Radiation Oncology, Fundação Centro de Controle de Oncologia Manaus- AM – sequence: 19 givenname: Ruffo orcidid: 0000-0003-4145-8598 surname: Freitas Junior fullname: Freitas Junior, Ruffo organization: . Mastology Program of the Goias Federal University, Goiânia-GO and representative of the Brazilian Mastology Society, São Paulo/SP, Brasil – sequence: 20 givenname: Harley Francisco de orcidid: 0000-0002-7408-5137 surname: Oliveira fullname: Oliveira, Harley Francisco de organization: . Centro de Tratamento em Radio-Oncologia (CTR) and Ribeirão Preto Medical School (FMRP) da Universidade de São Paulo (USP) - Ribeirão Preto/SP; Hospital Márcio Cunha (HMC) - Ipatinga/MG, Brasil |
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SubjectTerms | Brazil Breast - radiation effects Breast Neoplasms - pathology Breast Neoplasms - radiotherapy Carcinoma - pathology Carcinoma - radiotherapy Evidence-Based Medicine Female Humans Radiation Dose Hypofractionation - standards Risk Factors |
Title | Recommendations for hypofractionated whole-breast irradiation |
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