The antioxidant peptide SS31 prevents oxidative stress, downregulates CD36 and improves renal function in diabetic nephropathy

Oxidative stress plays an independent role in the pathogenesis of diabetic nephropathy (DN). CD36, a class B scavenger receptor, mediates reactive oxygen species (ROS) production in DN. SS31 is a mitochondria-targeted antioxidant peptide that can scavenge mitochondrial ROS. The antioxidative effects...

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Bibliographic Details
Published in:Nephrology, dialysis, transplantation Vol. 33; no. 11; pp. 1908 - 1918
Main Authors: Hou, Yanjuan, Shi, Yonghong, Han, Baosheng, Liu, Xuqian, Qiao, Xi, Qi, Yue, Wang, Lihua
Format: Journal Article
Language:English
Published: England 01-11-2018
Online Access:Get full text
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