Effect of recombinant human macrophage-colony stimulating factor on marrow, splenic, and peripheral hematopoietic progenitor cells in mice

The effects of human macrophage colony‐stimulating factor (M‐CSF) on marrow, splenic, and peripheral progenitor cells (CFU‐M, CFU‐GM, and CFU‐G) were investigated in mice administered recombinant human M‐CSF (8‐4,000 μg/kg). Single injection of 4,000 μg/kg of M‐CSF resulted in a decrease in the numb...

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Bibliographic Details
Published in:	Journal of leukocyte biology Vol. 59; no. 2; pp. 296 - 301
Main Authors:	Yamauchi, Takeshi, Yada, Kouji, Umemura, Akio, Asakura, Eiji, Hanamura, Takuji, Tanabe, Toshizumi
Format:	Journal Article
Language:	English
Published:	United States Society for Leukocyte Biology 01-02-1996
Subjects:	Animals Bone Marrow - drug effects Bone Marrow Cells Cell Movement - drug effects CHO Cells colony‐forming unit Cricetinae Erythrocytes - cytology Erythrocytes - drug effects Granulocytes - cytology Hematopoietic Stem Cells - drug effects Humans Leukocytes - cytology Leukocytes - drug effects Macrophage Colony-Stimulating Factor - pharmacology Male Mice Mice, Inbred C3H Phagocytes - cytology proliferation Recombinant Proteins - pharmacology Spleen - cytology Spleen - drug effects Stimulation, Chemical
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