The gene for catalase is assigned between the antigen loci MIC4 and MIC11

Genetic analysis of the cells of a WAGR patient (W, predisposition to Wilms tumor; A, aniridia; G, genitourinary abnormalities; R, mental retardation), bearing a partial deletion of band 11p13, was performed with biochemical and antigenic 11p markers by using gene dosage, somatic hybridization, mole...

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Bibliographic Details
Published in:	Genomics (San Diego, Calif.) Vol. 4; no. 1; p. 7
Main Authors:	Couillin, P, Azoulay, M, Metezeau, P, Grisard, M C, Junien, C
Format:	Journal Article
Language:	English
Published:	United States 01-01-1989
Subjects:	Antigens - genetics Catalase - genetics Child Chromosome Deletion Chromosome Mapping Chromosomes, Human, Pair 11 Female Genetic Markers Humans Intellectual Disability - genetics Iris - abnormalities Kidney Neoplasms - genetics Polymorphism, Genetic Syndrome Urogenital Abnormalities Wilms Tumor - genetics
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Summary:	Genetic analysis of the cells of a WAGR patient (W, predisposition to Wilms tumor; A, aniridia; G, genitourinary abnormalities; R, mental retardation), bearing a partial deletion of band 11p13, was performed with biochemical and antigenic 11p markers by using gene dosage, somatic hybridization, molecular hybridization, and indirect immunofluorescence techniques. These studies allowed the regional assignment of the gene for catalase, which is linked to the Wilms tumor locus, between MIC4 and MIC11, two loci encoding for membrane antigens previously mapped to band 11p13.
ISSN:	0888-7543
DOI:	10.1016/0888-7543(89)90307-8