Efficacy and Safety of Ertapenem Versus Piperacillin-Tazobactam for the Treatment of Intra-Abdominal Infections Requiring Surgical Intervention

Complicated intra-abdominal infections usually mandate prompt surgical intervention supplemented by appropriate antimicrobial therapy. The aim of this study was to demonstrate that ertapenem was not inferior to piperacillin-tazobactam for the treatment of community-acquired intra-abdominal infection...

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Bibliographic Details
Published in:	Journal of gastrointestinal surgery Vol. 10; no. 4; pp. 567 - 574
Main Authors:	Dela Pena, Arturo S., Asperger, Walter, Köckerling, Ferdinand, Raz, Raul, Kafka, Reinhold, Warren, Brian, Shivaprakash, Malathi, Vrijens, France, Giezek, Hilde, DiNubile, Mark J., Chan, Christina Y.
Format:	Journal Article
Language:	English
Published:	United States Elsevier Inc 01-04-2006 Springer Nature B.V
Subjects:	Abdomen Abdomen - microbiology Abscess - drug therapy Abscess - microbiology Abscess - surgery Adolescent Adult Aged Aged, 80 and over Alanine Transaminase - blood Anti-Bacterial Agents - adverse effects Anti-Bacterial Agents - therapeutic use Bacterial Infections - drug therapy Bacterial Infections - surgery Bacteroides fragilis Bacteroides Infections - drug therapy Bacteroides Infections - surgery beta-Lactams - adverse effects beta-Lactams - therapeutic use Diarrhea - chemically induced Drug therapy ertapenem Escherichia coli Infections - drug therapy Escherichia coli Infections - surgery Female Gastrointestinal Diseases - drug therapy Gastrointestinal Diseases - microbiology Gastrointestinal Diseases - surgery Humans Infections Intra-abdominal infection Male Middle Aged Penicillanic Acid - adverse effects Penicillanic Acid - analogs & derivatives Penicillanic Acid - therapeutic use Peritonitis - drug therapy Peritonitis - microbiology Peritonitis - surgery Piperacillin - adverse effects Piperacillin - therapeutic use piperacillin-tazobactam Prospective Studies Treatment Outcome Intra-abdominal infection piperacillin-tazobactam ertapenem
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