Blue light induced A2E oxidation in rat eyes--experimental animal model of dry AMD

Previous studies have shown that short-wavelength blue visible light induces retinal injury and may be a risk factor for age related macular degeneration. A2E is a blue light absorbing retinal chromophore that accumulates with age. Our previous in vitro studies have determined that, although A2E its...

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Bibliographic Details
Published in:	Photochemical & photobiological sciences Vol. 9; no. 11; p. 1505
Main Authors:	Wielgus, A R, Collier, R J, Martin, E, Lih, F B, Tomer, K B, Chignell, C F, Roberts, J E
Format:	Journal Article
Language:	English
Published:	England 01-11-2010
Subjects:	Animals Cholesterol - metabolism Disease Models, Animal Fatty Acids - metabolism Light - adverse effects Macular Degeneration - etiology Macular Degeneration - pathology Male Oxidation-Reduction Pyridinium Compounds - adverse effects Pyridinium Compounds - metabolism Rats Rats, Sprague-Dawley Retina - pathology Retina - radiation effects Retinoids - adverse effects Retinoids - metabolism
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