Systematic review with meta‐analysis: the adverse effects of tobacco smoking on the natural history of Crohn's disease
Summary Background Tobacco smoking is a well‐established risk factor for the development of Crohn's disease, and this may lead to a more complicated disease course. However, recent evidence suggests that many patients with Crohn's disease are unaware of this fact. Aim To perform a systemat...
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| Published in: | Alimentary pharmacology & therapeutics Vol. 43; no. 5; pp. 549 - 561 |
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| Main Authors: | , , |
| Format: | Journal Article |
| Language: | English |
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01-03-2016
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| Abstract | Summary
Background
Tobacco smoking is a well‐established risk factor for the development of Crohn's disease, and this may lead to a more complicated disease course. However, recent evidence suggests that many patients with Crohn's disease are unaware of this fact.
Aim
To perform a systematic review and meta‐analysis of the effects of smoking on disease course in Crohn's disease.
Methods
A search of MEDLINE, EMBASE and EMBASE classic was carried out (up to July 2015) to identify observational studies reporting data on smoking and rates of surgery or flares of disease activity in patients with Crohn's disease. Dichotomous data were pooled to obtain odds ratios (ORs) for flares of disease activity or need for surgery, with 95% confidence intervals (CIs).
Results
The search identified 33 eligible studies. Compared with nonsmokers, smokers had increased odds of flare of disease activity (OR, 1.56; 95% CI, 1.21–2.01), flare after surgery (OR, 1.97; 95% CI, 1.36–2.85), need for first surgery (OR, 1.68; 95% CI, 1.33–2.12) and need for second surgery (OR, 2.17; 95% CI, 1.63–2.89). The odds of these outcomes among ex‐smokers diminished upon smoking cessation, with ORs comparable to those among nonsmokers and, in the case of flare or second surgery, significantly lower than smokers.
Conclusions
Smokers with Crohn's disease have a more complicated disease course than nonsmokers, and quitting smoking may ameliorate this. Patients should be reminded of the detrimental effects of smoking on the course of their disease, and smoking cessation advice should be provided to reduce disease burden and costs in these patients. |
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| AbstractList | Tobacco smoking is a well-established risk factor for the development of Crohn's disease, and this may lead to a more complicated disease course. However, recent evidence suggests that many patients with Crohn's disease are unaware of this fact.
To perform a systematic review and meta-analysis of the effects of smoking on disease course in Crohn's disease.
A search of MEDLINE, EMBASE and EMBASE classic was carried out (up to July 2015) to identify observational studies reporting data on smoking and rates of surgery or flares of disease activity in patients with Crohn's disease. Dichotomous data were pooled to obtain odds ratios (ORs) for flares of disease activity or need for surgery, with 95% confidence intervals (CIs).
The search identified 33 eligible studies. Compared with nonsmokers, smokers had increased odds of flare of disease activity (OR, 1.56; 95% CI, 1.21-2.01), flare after surgery (OR, 1.97; 95% CI, 1.36-2.85), need for first surgery (OR, 1.68; 95% CI, 1.33-2.12) and need for second surgery (OR, 2.17; 95% CI, 1.63-2.89). The odds of these outcomes among ex-smokers diminished upon smoking cessation, with ORs comparable to those among nonsmokers and, in the case of flare or second surgery, significantly lower than smokers.
Smokers with Crohn's disease have a more complicated disease course than nonsmokers, and quitting smoking may ameliorate this. Patients should be reminded of the detrimental effects of smoking on the course of their disease, and smoking cessation advice should be provided to reduce disease burden and costs in these patients. BACKGROUNDTobacco smoking is a well-established risk factor for the development of Crohn's disease, and this may lead to a more complicated disease course. However, recent evidence suggests that many patients with Crohn's disease are unaware of this fact.AIMTo perform a systematic review and meta-analysis of the effects of smoking on disease course in Crohn's disease.METHODSA search of MEDLINE, EMBASE and EMBASE classic was carried out (up to July 2015) to identify observational studies reporting data on smoking and rates of surgery or flares of disease activity in patients with Crohn's disease. Dichotomous data were pooled to obtain odds ratios (ORs) for flares of disease activity or need for surgery, with 95% confidence intervals (CIs).RESULTSThe search identified 33 eligible studies. Compared with nonsmokers, smokers had increased odds of flare of disease activity (OR, 1.56; 95% CI, 1.21-2.01), flare after surgery (OR, 1.97; 95% CI, 1.36-2.85), need for first surgery (OR, 1.68; 95% CI, 1.33-2.12) and need for second surgery (OR, 2.17; 95% CI, 1.63-2.89). The odds of these outcomes among ex-smokers diminished upon smoking cessation, with ORs comparable to those among nonsmokers and, in the case of flare or second surgery, significantly lower than smokers.CONCLUSIONSSmokers with Crohn's disease have a more complicated disease course than nonsmokers, and quitting smoking may ameliorate this. Patients should be reminded of the detrimental effects of smoking on the course of their disease, and smoking cessation advice should be provided to reduce disease burden and costs in these patients. Summary Background Tobacco smoking is a well‐established risk factor for the development of Crohn's disease, and this may lead to a more complicated disease course. However, recent evidence suggests that many patients with Crohn's disease are unaware of this fact. Aim To perform a systematic review and meta‐analysis of the effects of smoking on disease course in Crohn's disease. Methods A search of MEDLINE , EMBASE and EMBASE classic was carried out (up to July 2015) to identify observational studies reporting data on smoking and rates of surgery or flares of disease activity in patients with Crohn's disease. Dichotomous data were pooled to obtain odds ratios ( OR s) for flares of disease activity or need for surgery, with 95% confidence intervals ( CI s). Results The search identified 33 eligible studies. Compared with nonsmokers, smokers had increased odds of flare of disease activity ( OR , 1.56; 95% CI , 1.21–2.01), flare after surgery ( OR , 1.97; 95% CI , 1.36–2.85), need for first surgery ( OR , 1.68; 95% CI , 1.33–2.12) and need for second surgery ( OR , 2.17; 95% CI , 1.63–2.89). The odds of these outcomes among ex‐smokers diminished upon smoking cessation, with OR s comparable to those among nonsmokers and, in the case of flare or second surgery, significantly lower than smokers. Conclusions Smokers with Crohn's disease have a more complicated disease course than nonsmokers, and quitting smoking may ameliorate this. Patients should be reminded of the detrimental effects of smoking on the course of their disease, and smoking cessation advice should be provided to reduce disease burden and costs in these patients. Summary Background Tobacco smoking is a well‐established risk factor for the development of Crohn's disease, and this may lead to a more complicated disease course. However, recent evidence suggests that many patients with Crohn's disease are unaware of this fact. Aim To perform a systematic review and meta‐analysis of the effects of smoking on disease course in Crohn's disease. Methods A search of MEDLINE, EMBASE and EMBASE classic was carried out (up to July 2015) to identify observational studies reporting data on smoking and rates of surgery or flares of disease activity in patients with Crohn's disease. Dichotomous data were pooled to obtain odds ratios (ORs) for flares of disease activity or need for surgery, with 95% confidence intervals (CIs). Results The search identified 33 eligible studies. Compared with nonsmokers, smokers had increased odds of flare of disease activity (OR, 1.56; 95% CI, 1.21–2.01), flare after surgery (OR, 1.97; 95% CI, 1.36–2.85), need for first surgery (OR, 1.68; 95% CI, 1.33–2.12) and need for second surgery (OR, 2.17; 95% CI, 1.63–2.89). The odds of these outcomes among ex‐smokers diminished upon smoking cessation, with ORs comparable to those among nonsmokers and, in the case of flare or second surgery, significantly lower than smokers. Conclusions Smokers with Crohn's disease have a more complicated disease course than nonsmokers, and quitting smoking may ameliorate this. Patients should be reminded of the detrimental effects of smoking on the course of their disease, and smoking cessation advice should be provided to reduce disease burden and costs in these patients. |
| Author | To, N. Ford, A. C. Gracie, D. J. |
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| BackLink | https://www.ncbi.nlm.nih.gov/pubmed/26749371$$D View this record in MEDLINE/PubMed |
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| Cites_doi | 10.1097/DCR.0b013e318222ddc3 10.1038/ajg.2011.70 10.1097/00054725-200411000-00019 10.1111/j.1365-2036.2012.05002.x 10.1111/j.1463-1318.2006.01202.x 10.1093/ecco-jcc/jju018 10.1016/j.crohns.2013.05.007 10.1007/BF02482360 10.1016/0016-5085(94)90697-1 10.1097/01.PSY.0000106907.24881.F2 10.1016/j.cgh.2007.09.002 10.2217/epi.11.22 10.1002/ibd.20029 10.1111/apt.13239 10.1136/gut.2004.041616 10.1007/s003840050215 10.1038/nri803 10.1097/MEG.0b013e32833036d9 10.1111/j.1365-2036.2011.04915.x 10.1002/sim.1186 10.1097/00004836-200301000-00005 10.1136/gut.2009.202101 10.1093/ecco-jcc/jjv113 10.1016/0016-5085(90)90324-T 10.1038/ajg.2011.64 10.1016/0197-2456(86)90046-2 10.1046/j.1365-2036.1999.00630.x 10.1136/jech.2004.019752 10.1111/apt.13423 10.1053/gast.2001.23231 10.1185/030079908X260790 10.1038/ajg.2009.387 10.1016/S0016-5085(98)70421-4 10.1016/j.surge.2015.04.002 10.1136/bmj.d4002 10.1002/ibd.3780040303 10.1016/S0749-3797(18)31021-3 10.1038/nature06005 10.1038/ajg.2010.317 10.1053/j.gastro.2011.10.001 10.1111/jgh.12369 10.1038/ajg.2014.300 10.1136/bmj.289.6450.954 10.1038/ajg.2011.71 10.1002/ibd.21889 10.1080/00365520600717496 10.1136/bmj.288.6414.362 10.1111/j.1365-2036.2005.02424.x 10.1016/j.crohns.2012.03.020 10.1016/j.cgh.2007.07.012 10.1016/S0016-5085(98)70419-6 10.1002/ibd.21864 10.1097/00004836-199207000-00005 10.1007/s00228-014-1702-1 10.1007/s00384-008-0542-9 10.1002/ibd.20828 10.1111/j.1572-0241.2007.01589.x 10.1016/j.crohns.2012.08.019 10.1136/gut.33.6.779 10.1111/j.1572-0241.2003.08674.x 10.1002/ibd.20220 10.1136/bmj.315.7109.629 10.1007/s10620-014-3368-z 10.3748/wjg.v11.i26.3971 10.1023/A:1026024829294 10.1097/00042737-199603000-00007 10.1038/ajg.2011.73 10.4065/81.11.1462 10.1038/ajg.2010.140 10.1016/j.amjsurg.2003.11.007 |
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| References | 2004; 66 1990; 98 2011a; 106 2014; 70 1997; 315 2010; 59 1984; 289 1984; 288 2010; 105 2005; 21 2011; 54 2012; 18 1998; 114 2008; 103 2014; 29 1992; 15 2013; 7 2013; 5 2003; 98 2013; 9 2014; 1 2010; 22 2003; 327 1994; 106 1986; 7 2015; 42 1999; 14 2011b; 106 1999; 13 2007; 9 2008; 23 2008; 24 2007; 5 2014; 9 2005; 39 1996; 8 2009; 15 2015; 13 2009; 66 2004; 187 2012; 142 2007; 448 2001; 120 2011d; 106 1999; 29 2013a; 8 2003; 36 2002; 2 2002; 80 2012; 35 2015; 9 2011; 3 1992; 33 2007; 13 2003; 253 2004; 10 2006; 81 2004; 53 2006; 41 2011; 106 2015; 60 2015; 110 2013b; 5 2005; 59 1998; 4 2011c; 106 2005; 11 2011; 343 1990; 6 2009; 104 27137733 - Aliment Pharmacol Ther. 2016 Jun;43(11):1245 27137736 - Aliment Pharmacol Ther. 2016 Jun;43(11):1247-8 27137735 - Aliment Pharmacol Ther. 2016 Jun;43(11):1246 27137737 - Aliment Pharmacol Ther. 2016 Jun;43(11):1248 Dam AN (e_1_2_7_61_1) 2013; 9 e_1_2_7_5_1 e_1_2_7_3_1 e_1_2_7_9_1 e_1_2_7_7_1 e_1_2_7_19_1 e_1_2_7_60_1 e_1_2_7_17_1 e_1_2_7_62_1 e_1_2_7_15_1 e_1_2_7_41_1 e_1_2_7_64_1 e_1_2_7_13_1 e_1_2_7_43_1 e_1_2_7_66_1 e_1_2_7_11_1 e_1_2_7_68_1 e_1_2_7_47_1 e_1_2_7_26_1 e_1_2_7_49_1 e_1_2_7_28_1 Radwan‐Kwiatek K (e_1_2_7_39_1) 2009; 66 e_1_2_7_73_1 e_1_2_7_50_1 e_1_2_7_71_1 Hughes JR (e_1_2_7_78_1) 2014; 1 e_1_2_7_25_1 e_1_2_7_31_1 e_1_2_7_52_1 e_1_2_7_77_1 e_1_2_7_23_1 e_1_2_7_33_1 e_1_2_7_75_1 e_1_2_7_21_1 e_1_2_7_35_1 e_1_2_7_56_1 e_1_2_7_37_1 Karczewski J (e_1_2_7_45_1) 2014; 9 e_1_2_7_6_1 e_1_2_7_4_1 e_1_2_7_8_1 e_1_2_7_18_1 e_1_2_7_16_1 e_1_2_7_40_1 e_1_2_7_82_1 e_1_2_7_2_1 e_1_2_7_14_1 e_1_2_7_42_1 e_1_2_7_63_1 e_1_2_7_12_1 e_1_2_7_44_1 e_1_2_7_65_1 e_1_2_7_10_1 e_1_2_7_46_1 e_1_2_7_67_1 e_1_2_7_48_1 e_1_2_7_69_1 Stead LF (e_1_2_7_81_1) 2013; 5 e_1_2_7_27_1 e_1_2_7_29_1 Stead LF (e_1_2_7_79_1) 2013; 8 Kane SV (e_1_2_7_54_1) 2005; 39 e_1_2_7_72_1 e_1_2_7_51_1 e_1_2_7_70_1 e_1_2_7_30_1 e_1_2_7_53_1 e_1_2_7_76_1 e_1_2_7_24_1 e_1_2_7_32_1 e_1_2_7_55_1 e_1_2_7_74_1 e_1_2_7_22_1 e_1_2_7_34_1 e_1_2_7_57_1 Cheikh I (e_1_2_7_58_1) 2002; 80 e_1_2_7_20_1 e_1_2_7_36_1 e_1_2_7_59_1 e_1_2_7_38_1 Cahill K (e_1_2_7_80_1) 2013; 5 |
| References_xml | – volume: 104 start-page: 2754 year: 2009 end-page: 9 article-title: Immunomodulators are associated with a lower risk of first surgery among patients with non‐penetrating non‐stricturing Crohn's disease publication-title: Am J Gastroenterol – volume: 18 start-page: 1101 year: 2012 end-page: 11 article-title: Current smoking differentially affects blood mononuclear cells from patients with Crohn's disease and ulcerative colitis: relevance to its adverse role in the disease publication-title: Inflamm Bowel Dis – volume: 106 start-page: 644 year: 2011a end-page: 59 article-title: Efficacy of biological therapies in inflammatory bowel disease: systematic review and meta‐analysis publication-title: Am J Gastroenterol – volume: 3 start-page: 267 year: 2011 end-page: 77 article-title: Epigenetics and lifestyle publication-title: Epigenomics – volume: 42 start-page: 1294 year: 2015 end-page: 302 article-title: Smoking behaviour and knowledge of the health effects of smoking in patients with inflammatory bowel disease publication-title: Aliment Pharmacol Ther – volume: 66 start-page: 567 year: 2009 end-page: 70 article-title: Impact of cigarette smoking on the clinical outcome of Crohn's disease publication-title: Przegl Lek – volume: 41 start-page: 1209 year: 2006 end-page: 11 article-title: Influence of smoking habits and CARD15 mutations on the onset of Crohn's disease publication-title: Scand J Gastroenterol – volume: 5 start-page: CD000165 year: 2013b article-title: Physician advice for smoking cessation publication-title: Cochrane Database Syst Rev – volume: 11 start-page: 3971 year: 2005 end-page: 9 article-title: Factors affecting recurrence after surgery for Crohn's disease publication-title: World J Gastroenterol – volume: 8 start-page: 225 year: 1996 end-page: 8 article-title: Effect of cigarette smoking on the course of Crohn's disease publication-title: Eur J Gastroenterol Hepatol – volume: 9 start-page: 819 year: 2015 end-page: 29 article-title: High rates of smoking especially in female Crohn's disease patients and low use of supportive measures to achieve smoking cessation‐data from the Swiss IBD cohort study publication-title: J Crohns Colitis – volume: 7 start-page: 280 year: 2013 end-page: 5 article-title: Does active smoking really influence the course of Crohn's disease? A retrospective observational study publication-title: J Crohns Colitis – volume: 10 start-page: 848 year: 2004 end-page: 59 article-title: Inflammatory bowel disease and smoking: a review of epidemiology, pathophysiology, and therapeutic implications publication-title: Inflamm Bowel Dis – volume: 54 start-page: 1147 year: 2011 end-page: 54 article-title: Clinical features and risk factors for primary surgery in 205 patients with Crohn's disease: analysis of a South China cohort publication-title: Dis Colon Rectum – volume: 9 start-page: 140 year: 2015 end-page: 6 article-title: Smoking and early infliximab response in Crohn's disease: a meta‐analysis publication-title: J Crohns Colitis – volume: 70 start-page: 907 year: 2014 end-page: 14 article-title: Efficacy and safety of adalimumab for the Crohn's disease: a systematic review and meta‐analysis of published randomized placebo‐controlled trials publication-title: Eur J Clin Pharmacol – volume: 13 start-page: 254 year: 2007 end-page: 61 article-title: Update on the incidence and prevalence of Crohn's disease and ulcerative colitis in Olmsted County, Minnesota, 1940‐2000 publication-title: Inflamm Bowel Dis – volume: 14 start-page: 224 year: 1999 end-page: 6 article-title: Operative and environmental risk factors for recurrence of Crohn's disease publication-title: Int J Colorectal Dis – volume: 13 start-page: 1369 year: 2007 end-page: 73 article-title: Long‐term clinical results of ileocecal resection for Crohn's disease publication-title: Inflamm Bowel Dis – volume: 7 start-page: 177 year: 1986 end-page: 88 article-title: Meta‐analysis in clinical trials publication-title: Control Clin Trials – volume: 6 start-page: 161 year: 1990 end-page: 6 article-title: Cigarette smoking and risk of clinical relapse in patients with Crohn's disease publication-title: Am J Prev Med – volume: 110 start-page: 368 year: 2015 end-page: 77 article-title: Funding a smoking cessation program for Crohn's disease: an economic evaluation publication-title: Am J Gastroenterol – volume: 24 start-page: 319 year: 2008 end-page: 28 article-title: The costs of Crohn's disease in the United States and other Western countries: a systematic review publication-title: Curr Med Res Opin – volume: 98 start-page: 2712 year: 2003 end-page: 8 article-title: Risk of early surgery for Crohn's disease: implications for early treatment strategies publication-title: Am J Gastroenterol – volume: 448 start-page: 427 year: 2007 end-page: 34 article-title: Unravelling the pathogenesis of inflammatory bowel disease publication-title: Nature – volume: 42 start-page: 61 year: 2015 end-page: 70 article-title: Smoking prevalence and its influence on disease course and surgery in Crohn's disease and ulcerative colitis publication-title: Aliment Pharmacol Ther – volume: 105 start-page: 1994 year: 2010 end-page: 2002 article-title: A prospective population‐based study of triggers of symptomatic flares in IBD publication-title: Am J Gastroenterol – volume: 289 start-page: 954 year: 1984 end-page: 6 article-title: Smoking and Crohn's disease publication-title: Br Med J (Clin Res Ed) – volume: 5 start-page: 1424 year: 2007 end-page: 9 article-title: The prevalence and geographic distribution of Crohn's disease and ulcerative colitis in the United States publication-title: Clin Gastroenterol Hepatol – volume: 7 start-page: 631 year: 2013 end-page: 5 article-title: Smoking and Crohn's disease: active modification of an independent risk factor (education alone is not enough) publication-title: J Crohns Colitis – volume: 15 start-page: 734 year: 2009 end-page: 41 article-title: Effects of light smoking consumption on the clinical course of Crohn's disease publication-title: Inflamm Bowel Dis – volume: 36 start-page: 8 year: 2003 end-page: 12 article-title: Clinical and demographic characterization of Jewish Crohn's disease patients in Israel publication-title: J Clin Gastroenterol – volume: 9 start-page: 567 year: 2007 end-page: 71 article-title: Early symptomatic recurrence after intestinal resection in Crohn's disease is unpredictable publication-title: Colorectal Dis – volume: 81 start-page: 1462 year: 2006 end-page: 71 article-title: Smoking and inflammatory bowel disease: a meta‐analysis publication-title: Mayo Clin Proc – volume: 35 start-page: 625 year: 2012 end-page: 33 article-title: Review article: the natural history of postoperative Crohn's disease recurrence publication-title: Aliment Pharmacol Ther – volume: 327 start-page: 557 year: 2003 end-page: 60 article-title: Measuring inconsistency in meta‐analyses publication-title: BMJ – volume: 29 start-page: 74 year: 2014 end-page: 82 article-title: Clinical features and predictors of clinical outcomes in Korean patients with Crohn's disease: a Korean association for the study of intestinal diseases multicenter study publication-title: J Gastroenterol Hepatol – volume: 60 start-page: 299 year: 2015 end-page: 312 article-title: The economic and quality‐of‐life burden of Crohn's disease in Europe and the United States, 2000 to 2013: a systematic review publication-title: Dig Dis Sci – volume: 315 start-page: 629 year: 1997 end-page: 34 article-title: Bias in meta‐analysis detected by a simple, graphical test publication-title: BMJ – volume: 288 start-page: 362 year: 1984 article-title: Should patients with inflammatory bowel disease smoke? publication-title: Br Med J (Clin Res Ed) – volume: 9 start-page: 711 year: 2013 end-page: 7 article-title: Environmental influences on the onset and clinical course of Crohn's disease‐part 1: an overview of external risk factors publication-title: Gastroenterol Hepatol (N Y) – volume: 59 start-page: 1200 year: 2010 end-page: 6 article-title: Natural history of Crohn's disease in a population‐based cohort from Cardiff (1986‐2003): a study of changes in medical treatment and surgical resection rates publication-title: Gut – volume: 5 start-page: CD009329 year: 2013 article-title: Pharmacological interventions for smoking cessation: an overview and network meta‐analysis publication-title: Cochrane Database Syst Rev – volume: 187 start-page: 219 year: 2004 end-page: 25 article-title: Crohn's disease patients who quit smoking have a reduced risk of reoperation for recurrence publication-title: Am J Surg – volume: 35 start-page: 126 year: 2012 end-page: 32 article-title: Co‐morbid diabetes in patients with Crohn's disease predicts a greater need for surgical intervention publication-title: Aliment Pharmacol Ther – volume: 106 start-page: 630 year: 2011 end-page: 42 article-title: Efficacy of immunosuppressive therapy for inflammatory bowel disease: a systematic review and meta‐analysis publication-title: Am J Gastroenterol – volume: 343 start-page: d4002 year: 2011 article-title: Recommendations for examining and interpreting funnel plot asymmetry in meta‐analyses of randomised controlled trials publication-title: BMJ – volume: 106 start-page: 617 year: 2011b end-page: 29 article-title: Efficacy of 5‐aminosalicylates in Crohn's disease: systematic review and meta‐analysis publication-title: Am J Gastroenterol – volume: 18 start-page: 1092 year: 2012 end-page: 100 article-title: Smokers with active Crohn's disease have a clinically relevant dysbiosis of the gastrointestinal microbiota publication-title: Inflamm Bowel Dis – volume: 21 start-page: 921 year: 2005 end-page: 31 article-title: Review article: smoking cessation as primary therapy to modify the course of Crohn's disease publication-title: Aliment Pharmacol Ther – volume: 103 start-page: 649 year: 2008 end-page: 55 article-title: The role of CARD15 mutations and smoking in the course of Crohn's disease in a Mediterranean area publication-title: Am J Gastroenterol – volume: 29 start-page: 579 year: 1999 end-page: 80 article-title: The association of cigarette smoking with a high risk of recurrence after ileocolonic resection for ileocecal Crohn's disease publication-title: Surg Today – volume: 80 start-page: 193 year: 2002 end-page: 8 article-title: Treatment and outcome of Crohn's disease without initial complications. Results of a retrospective, multicenter Tunisian study publication-title: Tunis Med – volume: 66 start-page: 79 year: 2004 end-page: 84 article-title: Impact of depressive mood on relapse in patients with inflammatory bowel disease: a prospective 18‐month follow‐up study publication-title: Psychosom Med – volume: 59 start-page: 63 year: 2005 end-page: 9 article-title: Work stress, smoking status, and smoking intensity: an observational study of 46, 190 employees publication-title: J Epidemiol Community Health – volume: 1 start-page: CD000031 year: 2014 article-title: Antidepressants for smoking cessation publication-title: Cochrane Database Syst Rev – volume: 120 start-page: 1093 year: 2001 end-page: 9 article-title: Smoking cessation and the course of Crohn's disease: an intervention study publication-title: Gastroenterology – volume: 13 start-page: 330 year: 2015 end-page: 47 article-title: Post‐operative recurrence in Crohn's disease. Critical analysis of potential risk factors. An update publication-title: Surgeon – volume: 5 start-page: 1430 year: 2007 end-page: 8 article-title: Clinical course in Crohn's disease: results of a Norwegian population‐based ten‐year follow‐up study publication-title: Clin Gastroenterol Hepatol – volume: 98 start-page: 1123 year: 1990 end-page: 8 article-title: Effect of cigarette smoking on recurrence of Crohn's disease publication-title: Gastroenterology – volume: 23 start-page: 1213 year: 2008 end-page: 21 article-title: The effect of smoking after surgery for Crohn's disease: a meta‐analysis of observational studies publication-title: Int J Colorectal Dis – volume: 106 start-page: 643 year: 1994 end-page: 8 article-title: Smoking habits and recurrence in Crohn's disease publication-title: Gastroenterology – volume: 106 start-page: 413 year: 2011d end-page: 20 article-title: 5‐aminosalicylates prevent relapse of Crohn's disease after surgically induced remission: systematic review and meta‐analysis publication-title: Am J Gastroenterol – volume: 7 start-page: e665 year: 2013 end-page: 71 article-title: Crohn's disease and smoking: is it ever too late to quit? publication-title: J Crohns Colitis – volume: 142 start-page: 46 year: 2012 end-page: 54 article-title: Increasing incidence and prevalence of the inflammatory bowel diseases with time, based on systematic review publication-title: Gastroenterology – volume: 2 start-page: 372 year: 2002 end-page: 7 article-title: Effects of cigarette smoke on the immune system publication-title: Nat Rev Immunol – volume: 253 start-page: 159 year: 2003 end-page: 65 article-title: Harmful health effects of cigarette smoking publication-title: Mol Cell Biochem – volume: 8 start-page: CD002850 year: 2013a article-title: Telephone counselling for smoking cessation publication-title: Cochrane Database Syst Rev – volume: 114 start-page: 1161 year: 1998 end-page: 8 article-title: Crohn's disease in Olmsted County, Minnesota, 1940‐1993: incidence, prevalence, and survival publication-title: Gastroenterology – volume: 106 start-page: 590 year: 2011c end-page: 9 article-title: Glucocorticosteroid therapy in inflammatory bowel disease: systematic review and meta‐analysis publication-title: Am J Gastroenterol – volume: 114 start-page: 1143 year: 1998 end-page: 50 article-title: Oral contraceptive use and smoking are risk factors for relapse in Crohn's disease. The Canadian Mesalamine for Remission of Crohn's Disease Study Group publication-title: Gastroenterology – volume: 33 start-page: 779 year: 1992 end-page: 82 article-title: Smoking in Crohn's disease: effect on localisation and clinical course publication-title: Gut – volume: 9 start-page: 153 year: 2014 end-page: 9 article-title: The effect of cigarette smoking on the clinical course of inflammatory bowel disease publication-title: Prz Gastroenterol – volume: 15 start-page: 12 year: 1992 end-page: 6 article-title: Factors influencing first relapse in patients with Crohn's disease publication-title: J Clin Gastroenterol – volume: 22 start-page: 872 year: 2010 end-page: 9 article-title: Early azathioprine/biological therapy is associated with decreased risk for first surgery and delays time to surgery but not reoperation in both smokers and nonsmokers with Crohn's disease, while smoking decreases the risk of colectomy in ulcerative colitis publication-title: Eur J Gastroenterol Hepatol – volume: 53 start-page: 1471 year: 2004 end-page: 8 article-title: Cost of illness of inflammatory bowel disease in the UK: a single centre retrospective study publication-title: Gut – volume: 4 start-page: 182 year: 1998 end-page: 6 article-title: Inflammatory bowel disease: is there any relation between smoking status and disease presentation? European Collaborative IBD Study Group publication-title: Inflamm Bowel Dis – volume: 13 start-page: 1403 year: 1999 end-page: 11 article-title: Effects of current and former cigarette smoking on the clinical course of Crohn's disease publication-title: Aliment Pharmacol Ther – volume: 39 start-page: 32 year: 2005 end-page: 5 article-title: Tobacco use is associated with accelerated clinical recurrence of Crohn's disease after surgically induced remission publication-title: J Clin Gastroenterol – ident: e_1_2_7_41_1 doi: 10.1097/DCR.0b013e318222ddc3 – ident: e_1_2_7_67_1 doi: 10.1038/ajg.2011.70 – ident: e_1_2_7_12_1 doi: 10.1097/00054725-200411000-00019 – ident: e_1_2_7_21_1 doi: 10.1111/j.1365-2036.2012.05002.x – ident: e_1_2_7_55_1 doi: 10.1111/j.1463-1318.2006.01202.x – ident: e_1_2_7_24_1 doi: 10.1093/ecco-jcc/jju018 – ident: e_1_2_7_14_1 doi: 10.1016/j.crohns.2013.05.007 – ident: e_1_2_7_48_1 doi: 10.1007/BF02482360 – ident: e_1_2_7_51_1 doi: 10.1016/0016-5085(94)90697-1 – ident: e_1_2_7_60_1 doi: 10.1097/01.PSY.0000106907.24881.F2 – ident: e_1_2_7_38_1 doi: 10.1016/j.cgh.2007.09.002 – volume: 66 start-page: 567 year: 2009 ident: e_1_2_7_39_1 article-title: Impact of cigarette smoking on the clinical outcome of Crohn's disease publication-title: Przegl Lek contributor: fullname: Radwan‐Kwiatek K – ident: e_1_2_7_72_1 doi: 10.2217/epi.11.22 – ident: e_1_2_7_2_1 doi: 10.1002/ibd.20029 – ident: e_1_2_7_59_1 doi: 10.1111/apt.13239 – ident: e_1_2_7_8_1 doi: 10.1136/gut.2004.041616 – ident: e_1_2_7_47_1 doi: 10.1007/s003840050215 – ident: e_1_2_7_71_1 doi: 10.1038/nri803 – ident: e_1_2_7_40_1 doi: 10.1097/MEG.0b013e32833036d9 – ident: e_1_2_7_34_1 doi: 10.1111/j.1365-2036.2011.04915.x – ident: e_1_2_7_28_1 doi: 10.1002/sim.1186 – ident: e_1_2_7_32_1 doi: 10.1097/00004836-200301000-00005 – ident: e_1_2_7_65_1 doi: 10.1136/gut.2009.202101 – ident: e_1_2_7_77_1 doi: 10.1093/ecco-jcc/jjv113 – ident: e_1_2_7_46_1 doi: 10.1016/0016-5085(90)90324-T – ident: e_1_2_7_27_1 – volume: 5 start-page: CD000165 year: 2013 ident: e_1_2_7_81_1 article-title: Physician advice for smoking cessation publication-title: Cochrane Database Syst Rev contributor: fullname: Stead LF – volume: 39 start-page: 32 year: 2005 ident: e_1_2_7_54_1 article-title: Tobacco use is associated with accelerated clinical recurrence of Crohn's disease after surgically induced remission publication-title: J Clin Gastroenterol contributor: fullname: Kane SV – ident: e_1_2_7_63_1 doi: 10.1038/ajg.2011.64 – volume: 9 start-page: 711 year: 2013 ident: e_1_2_7_61_1 article-title: Environmental influences on the onset and clinical course of Crohn's disease‐part 1: an overview of external risk factors publication-title: Gastroenterol Hepatol (N Y) contributor: fullname: Dam AN – volume: 9 start-page: 153 year: 2014 ident: e_1_2_7_45_1 article-title: The effect of cigarette smoking on the clinical course of inflammatory bowel disease publication-title: Prz Gastroenterol contributor: fullname: Karczewski J – ident: e_1_2_7_29_1 doi: 10.1016/0197-2456(86)90046-2 – ident: e_1_2_7_15_1 doi: 10.1046/j.1365-2036.1999.00630.x – ident: e_1_2_7_62_1 doi: 10.1136/jech.2004.019752 – volume: 5 start-page: CD009329 year: 2013 ident: e_1_2_7_80_1 article-title: Pharmacological interventions for smoking cessation: an overview and network meta‐analysis publication-title: Cochrane Database Syst Rev contributor: fullname: Cahill K – ident: e_1_2_7_73_1 doi: 10.1111/apt.13423 – ident: e_1_2_7_13_1 doi: 10.1053/gast.2001.23231 – volume: 80 start-page: 193 year: 2002 ident: e_1_2_7_58_1 article-title: Treatment and outcome of Crohn's disease without initial complications. Results of a retrospective, multicenter Tunisian study publication-title: Tunis Med contributor: fullname: Cheikh I – ident: e_1_2_7_7_1 doi: 10.1185/030079908X260790 – ident: e_1_2_7_43_1 doi: 10.1038/ajg.2009.387 – ident: e_1_2_7_3_1 doi: 10.1016/S0016-5085(98)70421-4 – ident: e_1_2_7_19_1 doi: 10.1016/j.surge.2015.04.002 – ident: e_1_2_7_31_1 doi: 10.1136/bmj.d4002 – ident: e_1_2_7_16_1 doi: 10.1002/ibd.3780040303 – ident: e_1_2_7_37_1 doi: 10.1016/S0749-3797(18)31021-3 – volume: 8 start-page: CD002850 year: 2013 ident: e_1_2_7_79_1 article-title: Telephone counselling for smoking cessation publication-title: Cochrane Database Syst Rev contributor: fullname: Stead LF – ident: e_1_2_7_9_1 doi: 10.1038/nature06005 – ident: e_1_2_7_68_1 doi: 10.1038/ajg.2010.317 – ident: e_1_2_7_5_1 doi: 10.1053/j.gastro.2011.10.001 – ident: e_1_2_7_44_1 doi: 10.1111/jgh.12369 – ident: e_1_2_7_82_1 doi: 10.1038/ajg.2014.300 – ident: e_1_2_7_10_1 doi: 10.1136/bmj.289.6450.954 – volume: 1 start-page: CD000031 year: 2014 ident: e_1_2_7_78_1 article-title: Antidepressants for smoking cessation publication-title: Cochrane Database Syst Rev contributor: fullname: Hughes JR – ident: e_1_2_7_66_1 doi: 10.1038/ajg.2011.71 – ident: e_1_2_7_70_1 doi: 10.1002/ibd.21889 – ident: e_1_2_7_56_1 doi: 10.1080/00365520600717496 – ident: e_1_2_7_11_1 doi: 10.1136/bmj.288.6414.362 – ident: e_1_2_7_26_1 doi: 10.1111/j.1365-2036.2005.02424.x – ident: e_1_2_7_35_1 doi: 10.1016/j.crohns.2012.03.020 – ident: e_1_2_7_4_1 doi: 10.1016/j.cgh.2007.07.012 – ident: e_1_2_7_17_1 doi: 10.1016/S0016-5085(98)70419-6 – ident: e_1_2_7_69_1 doi: 10.1002/ibd.21864 – ident: e_1_2_7_52_1 doi: 10.1097/00004836-199207000-00005 – ident: e_1_2_7_25_1 doi: 10.1007/s00228-014-1702-1 – ident: e_1_2_7_20_1 doi: 10.1007/s00384-008-0542-9 – ident: e_1_2_7_33_1 doi: 10.1002/ibd.20828 – ident: e_1_2_7_42_1 doi: 10.1111/j.1572-0241.2007.01589.x – ident: e_1_2_7_75_1 – ident: e_1_2_7_74_1 doi: 10.1016/j.crohns.2012.08.019 – ident: e_1_2_7_36_1 doi: 10.1136/gut.33.6.779 – ident: e_1_2_7_18_1 doi: 10.1111/j.1572-0241.2003.08674.x – ident: e_1_2_7_49_1 doi: 10.1002/ibd.20220 – ident: e_1_2_7_30_1 doi: 10.1136/bmj.315.7109.629 – ident: e_1_2_7_6_1 doi: 10.1007/s10620-014-3368-z – ident: e_1_2_7_22_1 doi: 10.3748/wjg.v11.i26.3971 – ident: e_1_2_7_76_1 doi: 10.1023/A:1026024829294 – ident: e_1_2_7_50_1 doi: 10.1097/00042737-199603000-00007 – ident: e_1_2_7_64_1 doi: 10.1038/ajg.2011.73 – ident: e_1_2_7_23_1 doi: 10.4065/81.11.1462 – ident: e_1_2_7_53_1 doi: 10.1038/ajg.2010.140 – ident: e_1_2_7_57_1 doi: 10.1016/j.amjsurg.2003.11.007 |
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Background
Tobacco smoking is a well‐established risk factor for the development of Crohn's disease, and this may lead to a more complicated disease... Tobacco smoking is a well-established risk factor for the development of Crohn's disease, and this may lead to a more complicated disease course. However,... BackgroundTobacco smoking is a well‐established risk factor for the development of Crohn's disease, and this may lead to a more complicated disease course.... BACKGROUNDTobacco smoking is a well-established risk factor for the development of Crohn's disease, and this may lead to a more complicated disease course.... |
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| SubjectTerms | Cigarette smoking Crohn Disease - physiopathology Crohn Disease - surgery Crohn's disease Crohns disease Disease Progression Drug addiction Flares Health risk assessment Humans Meta-analysis Risk Factors Smoking Smoking - adverse effects Smoking cessation Surgery Systematic review Tobacco Tobacco smoking |
| Title | Systematic review with meta‐analysis: the adverse effects of tobacco smoking on the natural history of Crohn's disease |
| URI | https://onlinelibrary.wiley.com/doi/abs/10.1111%2Fapt.13511 https://www.ncbi.nlm.nih.gov/pubmed/26749371 https://www.proquest.com/docview/2300613704 https://search.proquest.com/docview/1762962560 |
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