Embryonic inhibition of colony‐stimulating factor 1 receptor impacts craniofacial morphogenesis

Objectives Colony‐stimulating factor‐1 receptor (CSF1R) is vital for the recruitment of monocytes, and their proliferation and differentiation into functional osteoclasts. Mouse studies, where CSF1R and its cognate ligand are absent, have significant craniofacial phenotypes, but these have not been...

Full description

Saved in:

Bibliographic Details
Published in:	Orthodontics & craniofacial research Vol. 26; no. S1; pp. 20 - 28
Main Authors:	Nagra, Ashina, Katsube, Motoki, Gao, Wade, Rosin, Jessica M., Vora, Siddharth R.
Format:	Journal Article
Language:	English
Published:	England Wiley Subscription Services, Inc 01-12-2023
Subjects:	Animals Computed tomography craniofacial morphogenesis CSF1R Dental caries embryonic development Embryos Female geometric morphometrics Immunofluorescence Jaw Juveniles Macrophage Colony-Stimulating Factor - pharmacology Mandible Mandible - metabolism Mice Monocytes Morphogenesis Osteoclastogenesis Osteoclasts Phenotypes Pregnancy Skull Skull - diagnostic imaging Skull - metabolism X-Ray Microtomography CSF1R craniofacial morphogenesis embryonic development geometric morphometrics osteoclasts
Online Access:	Get full text
Tags:	Add Tag No Tags, Be the first to tag this record!

Be the first to leave a comment!