Presence of Gumprecht shadows (smudge cells) in bovine leukemia virus-positive cattle
•Enzootic Bovine Leukosis is a chronic disease caused by the bovine leukemia virus (BLV).•Blood smears of BLV-infected and non-infected cattle were stained and analyzed.•We report the presence of Gumprecht shadows in peripheral blood of BLV positive cattle. Enzootic Bovine Leukosis is a chronic dise...
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Published in: | Journal of virological methods Vol. 193; no. 2; pp. 519 - 520 |
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01-11-2013
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Abstract | •Enzootic Bovine Leukosis is a chronic disease caused by the bovine leukemia virus (BLV).•Blood smears of BLV-infected and non-infected cattle were stained and analyzed.•We report the presence of Gumprecht shadows in peripheral blood of BLV positive cattle.
Enzootic Bovine Leukosis is a chronic disease caused by the bovine leukemia virus (BLV). Smudge cells, also known as Gumprecht shadows, are not simple artifacts of slide preparation, but ragged lymphoid cells found mainly in peripheral blood smears from human patients with chronic lymphocytic leukemia. In this study, we report the presence of Gumprecht shadows in peripheral blood from BLV-positive cattle. |
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AbstractList | Enzootic Bovine Leukosis is a chronic disease caused by the bovine leukemia virus (BLV). Smudge cells, also known as Gumprecht shadows, are not simple artifacts of slide preparation, but ragged lymphoid cells found mainly in peripheral blood smears from human patients with chronic lymphocytic leukemia. In this study, we report the presence of Gumprecht shadows in peripheral blood from BLV-positive cattle. •Enzootic Bovine Leukosis is a chronic disease caused by the bovine leukemia virus (BLV).•Blood smears of BLV-infected and non-infected cattle were stained and analyzed.•We report the presence of Gumprecht shadows in peripheral blood of BLV positive cattle. Enzootic Bovine Leukosis is a chronic disease caused by the bovine leukemia virus (BLV). Smudge cells, also known as Gumprecht shadows, are not simple artifacts of slide preparation, but ragged lymphoid cells found mainly in peripheral blood smears from human patients with chronic lymphocytic leukemia. In this study, we report the presence of Gumprecht shadows in peripheral blood from BLV-positive cattle. |
Author | Panei, Carlos Javier Echeverría, María Gabriela González, Ester Teresa Larsen, Alejandra |
Author_xml | – sequence: 1 givenname: Carlos Javier surname: Panei fullname: Panei, Carlos Javier organization: Virology, Faculty of Veterinary Sciences, National University of La Plata, 60 and 118, CC 296, 1900 La Plata, Argentina – sequence: 2 givenname: Alejandra surname: Larsen fullname: Larsen, Alejandra organization: Virology, Faculty of Veterinary Sciences, National University of La Plata, 60 and 118, CC 296, 1900 La Plata, Argentina – sequence: 3 givenname: Ester Teresa surname: González fullname: González, Ester Teresa organization: Virology, Faculty of Veterinary Sciences, National University of La Plata, 60 and 118, CC 296, 1900 La Plata, Argentina – sequence: 4 givenname: María Gabriela surname: Echeverría fullname: Echeverría, María Gabriela email: gecheverria@fcv.unlp.edu.ar, mariagabrielaecheverria@yahoo.com.ar organization: Virology, Faculty of Veterinary Sciences, National University of La Plata, 60 and 118, CC 296, 1900 La Plata, Argentina |
BackLink | https://www.ncbi.nlm.nih.gov/pubmed/23886563$$D View this record in MEDLINE/PubMed |
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Cites_doi | 10.1016/S0378-1135(03)00202-5 10.1128/JVI.63.5.2099-2107.1989 10.5858/2003-127-105-PGOTRO 10.4049/jimmunol.166.11.6640 10.1200/JCO.2008.17.0795 |
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Keywords | Enzootic bovine leukosis Gumprecht shadows |
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References | Gumprecht (bib0010) 1896; 57 Brown, Hallam, Colucci-Guyon, Shaw (bib0005) 2001; 166 Miller, Miller, Olson, Gillette (bib0035) 1969; 43 Nowakowski, Hoyer, Shanafelt, Zent, Call, Bone, Laplant, Dewald, Tschumper, Jelinek, Witzig, Kay (bib0040) 2009; 27 Heinivaara (bib0015) 1959; 48 Licursi, Inoshima, Wu, Yokoyama, González, Sentsui (bib0025) 2003; 96 Lagarias, Radke (bib0020) 1989; 63 Macdonald, Richardson, Raby (bib0030) 2003; 127 Nowakowski (10.1016/j.jviromet.2013.07.022_bib0040) 2009; 27 Lagarias (10.1016/j.jviromet.2013.07.022_bib0020) 1989; 63 Licursi (10.1016/j.jviromet.2013.07.022_bib0025) 2003; 96 Gumprecht (10.1016/j.jviromet.2013.07.022_bib0010) 1896; 57 Heinivaara (10.1016/j.jviromet.2013.07.022_bib0015) 1959; 48 Macdonald (10.1016/j.jviromet.2013.07.022_bib0030) 2003; 127 Miller (10.1016/j.jviromet.2013.07.022_bib0035) 1969; 43 Brown (10.1016/j.jviromet.2013.07.022_bib0005) 2001; 166 |
References_xml | – volume: 48 start-page: 69 year: 1959 end-page: 75 ident: bib0015 article-title: Smudge cells in lymphocytic leukemia publication-title: Annales Medicinae Internae Fenniae contributor: fullname: Heinivaara – volume: 166 start-page: 6640 year: 2001 end-page: 6646 ident: bib0005 article-title: Rigidity of circulating lymphocytes is primarily conferred by vimentin intermediate filaments publication-title: Journal of Immunology contributor: fullname: Shaw – volume: 127 start-page: 105 year: 2003 ident: bib0030 article-title: Practice guidelines on the reporting of smudge cells in the white blood cell differential count publication-title: Archives of Pathology & Laboratory Medicine contributor: fullname: Raby – volume: 43 start-page: 1297 year: 1969 end-page: 1305 ident: bib0035 article-title: Virus-like particles in phytohemagglutinin-stimulated lymphocyte cultures with reference to bovine lymphosarcoma publication-title: Journal of the National Cancer Institute contributor: fullname: Gillette – volume: 57 start-page: 523 year: 1896 end-page: 548 ident: bib0010 article-title: Leukozytenzerfall im Blute bei Leukamie und bei schweren Anamien publication-title: Deutsch Arch. Klini. Med. contributor: fullname: Gumprecht – volume: 63 start-page: 2099 year: 1989 end-page: 2107 ident: bib0020 article-title: Transcriptional activation of bovine leukemia virus in blood cells from experimentally infected, asymptomatic sheep with latent infections publication-title: Journal of Virology contributor: fullname: Radke – volume: 96 start-page: 17 year: 2003 end-page: 23 ident: bib0025 article-title: Provirus variants of bovine leukemia virus in naturally infected cattle from Argentina and Japan publication-title: Veterinary Microbiology contributor: fullname: Sentsui – volume: 27 start-page: 1844 year: 2009 end-page: 1849 ident: bib0040 article-title: Percentage of smudge cells on routine blood smear predicts survival in chronic lymphocytic leukemia publication-title: Journal of Clinical Oncology contributor: fullname: Kay – volume: 96 start-page: 17 year: 2003 ident: 10.1016/j.jviromet.2013.07.022_bib0025 article-title: Provirus variants of bovine leukemia virus in naturally infected cattle from Argentina and Japan publication-title: Veterinary Microbiology doi: 10.1016/S0378-1135(03)00202-5 contributor: fullname: Licursi – volume: 63 start-page: 2099 year: 1989 ident: 10.1016/j.jviromet.2013.07.022_bib0020 article-title: Transcriptional activation of bovine leukemia virus in blood cells from experimentally infected, asymptomatic sheep with latent infections publication-title: Journal of Virology doi: 10.1128/JVI.63.5.2099-2107.1989 contributor: fullname: Lagarias – volume: 127 start-page: 105 year: 2003 ident: 10.1016/j.jviromet.2013.07.022_bib0030 article-title: Practice guidelines on the reporting of smudge cells in the white blood cell differential count publication-title: Archives of Pathology & Laboratory Medicine doi: 10.5858/2003-127-105-PGOTRO contributor: fullname: Macdonald – volume: 43 start-page: 1297 year: 1969 ident: 10.1016/j.jviromet.2013.07.022_bib0035 article-title: Virus-like particles in phytohemagglutinin-stimulated lymphocyte cultures with reference to bovine lymphosarcoma publication-title: Journal of the National Cancer Institute contributor: fullname: Miller – volume: 48 start-page: 69 year: 1959 ident: 10.1016/j.jviromet.2013.07.022_bib0015 article-title: Smudge cells in lymphocytic leukemia publication-title: Annales Medicinae Internae Fenniae contributor: fullname: Heinivaara – volume: 166 start-page: 6640 year: 2001 ident: 10.1016/j.jviromet.2013.07.022_bib0005 article-title: Rigidity of circulating lymphocytes is primarily conferred by vimentin intermediate filaments publication-title: Journal of Immunology doi: 10.4049/jimmunol.166.11.6640 contributor: fullname: Brown – volume: 57 start-page: 523 year: 1896 ident: 10.1016/j.jviromet.2013.07.022_bib0010 article-title: Leukozytenzerfall im Blute bei Leukamie und bei schweren Anamien publication-title: Deutsch Arch. Klini. Med. contributor: fullname: Gumprecht – volume: 27 start-page: 1844 year: 2009 ident: 10.1016/j.jviromet.2013.07.022_bib0040 article-title: Percentage of smudge cells on routine blood smear predicts survival in chronic lymphocytic leukemia publication-title: Journal of Clinical Oncology doi: 10.1200/JCO.2008.17.0795 contributor: fullname: Nowakowski |
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Snippet | •Enzootic Bovine Leukosis is a chronic disease caused by the bovine leukemia virus (BLV).•Blood smears of BLV-infected and non-infected cattle were stained and... Enzootic Bovine Leukosis is a chronic disease caused by the bovine leukemia virus (BLV). Smudge cells, also known as Gumprecht shadows, are not simple... |
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SubjectTerms | Animals blood Bovine leukemia virus Cattle chronic diseases Enzootic bovine leukosis Enzootic Bovine Leukosis - pathology Enzootic Bovine Leukosis - virology Gumprecht shadows Leukemia Virus, Bovine - isolation & purification Leukocytes, Mononuclear - cytology lymphocytic leukemia patients |
Title | Presence of Gumprecht shadows (smudge cells) in bovine leukemia virus-positive cattle |
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