Sonographically guided puncture of pancreatic lesions: a low number of needle passes does not compromise the diagnostic yield

• Published in: Journal of medical ultrasonics (2001) Vol. 41; no. 1; pp. 111 - 112
• Main Authors: Di Vece, Francesca, Tombesi, Paola, Ermili, Francesca, Abbasciano, Vincenzo, Sartori, Sergio
• Format: Journal Article
• Language: English
• Published: Tokyo Springer Japan 01-01-2014; Springer; Springer Nature B.V
• Subjects: Biopsy; Cancer; Cellular biology; Cysts; Cytology; Diagnostic systems; Imaging; Lesions; Letter to the Editor; Medicine; Medicine & Public Health; Metastasis; Pancreas; Radiology; Ultrasonic imaging; Ultrasound; United States > US; Italy; Touch preparation cytology; Puncture; Pancreas; Complications; Biopsy; Ultrasonography
• ISSN: 1346-4523; 1613-2254
• DOI: 10.1007/s10396-013-0458-z

Sensitivity, specificity, positive predictive value, negative predictive value, and overall diagnostic accuracy of CNB combined with touch preparation cytology were 98, 100, 100, 95.1, and 98.6 %, respectively, excluding the two inadequate specimens from the analysis; and 96.2, 100, 100, 90.7, and 97.2 %, respectively, including the two inadequate specimens as false negatives into an intention-to-treat analysis. Results of 143 core needle biopsies of pancreatic solid or mixed lesions Biopsy result Number of cases (%) Adenocarcinoma 54 (37.8) Neuroendocrine neoplasia 17 (11.9) Undetermined carcinoma 14 (9.8) Lymphoma 6 (4.2) Metastatic renal cancer 4 (2.8) Mucinous cystadenocarcinoma 2 (1.4) Liposarcoma 2 (1.4) Fibrosarcoma 1 (0.7) Chronic pancreatitis 30 (20.9) Organized pseudocyst 5 (3.5) Serous cystadenoma 3 (2.1) Amyloid tumor 1 (0.7) False negative (normal pancreatic tissue, surgical diagnosis: adenocarcinoma) 2 (1.4) Inadequate specimen 2 (1.4) Total 143 In accordance with many prior reports, our experience confirms the safety of PP of pancreatic lesions. [...]it suggests that the procedure can be well tolerated with no need for intravenous premedication, and can be performed with just one or two needle passes without compromising the diagnostic yield. The low number of complications of pancreatic PP reported in the literature does not enable the identification of potential risk factors of complications, even though it is reasonable to hypothesize that the number of needle passes might represent an at least theoretical risk factor.